Semi-automated computed tomography Volumetry can predict hemihepatectomy specimens' volumes in patients with hepatic malignancy

• Verfasst von: Mayer, Philipp [VerfasserIn]
• Verfasst von: Grözinger, Martin [VerfasserIn]
• Verfasst von: Mokry, Theresa [VerfasserIn]
• Verfasst von: Schemmer, Peter [VerfasserIn]
• Verfasst von: Waldburger, Nina [VerfasserIn]
• Verfasst von: Kauczor, Hans-Ulrich [VerfasserIn]
• Verfasst von: Klauß, Miriam [VerfasserIn]
• Verfasst von: Sommer, Christof-Matthias [VerfasserIn]
• Titel: Semi-automated computed tomography Volumetry can predict hemihepatectomy specimens' volumes in patients with hepatic malignancy
• Verf.angabe: Philipp Mayer, Martin Grözinger, Theresa Mokry, Peter Schemmer, Nina Waldburger, Hans-Ulrich Kauczor, Miriam Klauss and Christof-Matthias Sommer
• E-Jahr: 2019
• Jahr: 26 February 2019
• Umfang: 11 S.
• Fussnoten: Gesehen am 08.04.2019
• Titel Quelle: Enthalten in: BMC medical imaging
• Ort Quelle: London : BioMed Central, 2001
• Jahr Quelle: 2019
• Band/Heft Quelle: 19(2019), Artikel-ID 20, Seite 1-11
• ISSN Quelle: 1471-2342
• DOI: doi:10.1186/s12880-019-0309-5
• Datenträger: Online-Ressource
• Sprache: eng
• Sach-SW: Computed tomography volumetry
• Sach-SW: ct-volumetry
• Sach-SW: donor liver-transplantation
• Sach-SW: dysfunction
• Sach-SW: Hemihepatectomy
• Sach-SW: Hepatic malignancy
• Sach-SW: remnant
• Sach-SW: slice thickness
• Sach-SW: weight
• K10plus-PPN: 1662963777

Abstract

BackgroundOne of the major causes of perioperative mortality of patients undergoing major hepatic resections is post-hepatectomy liver failure (PHLF). For preoperative appraisal of the risk of PHLF it is important to accurately predict resectate volume and future liver remnant volume (FLRV). The objective of our study is to prospectively evaluate the accuracy of hemihepatectomy resectate volumes that are determined by computed tomography volumetry (CTV) when compared with intraoperatively measured volumes and weights as gold standard in patients undergoing hemihepatectomy.MethodsTwenty four patients (13 women, 11 men) scheduled for hemihepatectomy due to histologically proven primary or secondary hepatic malignancies were included in our study. CTV was performed using a semi-automated module (S, hereinafter) (syngo.CT Liver Analysis VA30, Siemens Healthcare, Germany). Conversion factors between CT volumes on the one side and intraoperative volumes and weights on the other side were calculated using the method of least squares. Absolute and relative disagreements between CT volumes and intraoperative volumes were determined.ResultsA conversion factor of c=0.906 most precisely predicted intraoperative volumes of exsanguinated hemihepatectomy specimens from CT volumes in all patients with mean absolute and relative disagreements between CT volumes and intraoperative volumes of 57ml and 6.3%. The use of operation-specific conversion factors yielded even better results.ConclusionsCTV performed with S accurately predicts intraoperative volumes of hemihepatectomy specimens when applying conversion factors which compensate for exsanguination. This allows to precisely estimate the FLRV and thus minimize the risk of PHLF in patients undergoing major hepatic resections.