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Status: Bibliographieeintrag

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Verfasst von:Wolff, Michael von [VerfasserIn]   i
 Bruckner, Thomas [VerfasserIn]   i
 Strowitzki, Thomas [VerfasserIn]   i
 Germeyer, Ariane [VerfasserIn]   i
Titel:Fertility preservation
Titelzusatz:ovarian response to freeze oocytes is not affected by different malignant diseases-an analysis of 992 stimulations
Verf.angabe:M. von Wolff, T. Bruckner, T. Strowitzki, A. Germeyer
E-Jahr:2018
Jahr:05 June 2018
Umfang:7 S.
Fussnoten:Gesehen am 09.04.2019
Titel Quelle:Enthalten in: Journal of assisted reproduction and genetics
Ort Quelle:Dordrecht [u.a.] : Springer Science + Business Media B.V., 1984
Jahr Quelle:2018
Band/Heft Quelle:35(2018), 9, Seite 1713-1719
ISSN Quelle:1573-7330
Abstract:PURPOSE: To study if ovarian response is affected by the type of disease if fertility preservation is required. - METHODS: A registry of the trinational fertility preservation network FertiPROTEKT including 992 patients aged 18-40 years undergoing ovarian stimulation and follicle aspiration for fertility preservation from 1/2007 until 3/2016 was analysed. The number of collected oocytes, days of stimulation, total gonadotropin dosage and gonadotropin dosage per day were evaluated. - RESULTS: Total oocyte number was negatively correlated with increasing age (r = 0.237, p < 0.0001). Oocyte numbers were in women < 26 years 15.4 ± 8.8, 26-30 years 13.1 ± 8.5, 31-35 years 12.2 ± 7.7 and 36-40 years 9.9 ± 8.0. Age-adjusted oocyte numbers were not different in women with Hodgkin's lymphoma (12.6 ± 8.8), non-Hodgkin's lymphoma (12.4 ± 8.2), leukaemia (11.7 ± 8.2), sarcoma (11.8 ± 8.2), cerebral cancer (16.5 ± 8.1), gastrointestinal cancer (13.2 ± 8.1) gynaecological cancer (10.8 ± 8.2) and other types of malignancies (15.8 ± 8.1) apart from ovarian cancer with lower oocyte yield (7.3 ± 8.3, p < 0.001) compared to women with breast cancer (13.3 ± 8.8). The total gonadotropin dose used for stimulation was only elevated in Hodgkin's and non-Hodgkin's lymphoma compared to women with breast cancer (p < 0.05). Oocyte yield was lower in women with versus without ovarian cancer (p < 0.0001). - CONCLUSIONS: As ovarian response is not affected by the type of cancer, ovarian stimulation can be performed with the same oocyte yield in different malignant diseases. However, oocyte yield is reduced if ovarian surgery is required and in older women.
DOI:doi:10.1007/s10815-018-1227-0
URL:Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.

Volltext: http://dx.doi.org/10.1007/s10815-018-1227-0
 DOI: https://doi.org/10.1007/s10815-018-1227-0
Datenträger:Online-Ressource
Sprache:eng
Sach-SW:Adolescent
 Adult
 Breast cancer
 Breast Neoplasms
 Cryopreservation
 Female
 Fertility preservation
 Fertility Preservation
 Hodgkin Disease
 Hodgkin’s lymphoma
 Humans
 Oocyte
 Oocyte Retrieval
 Oocytes
 Ovarian cancer
 Ovarian Neoplasms
 Ovarian stimulation
 Ovary
 Ovulation Induction
 Pregnancy
 Young Adult
K10plus-PPN:1662999356
Verknüpfungen:→ Zeitschrift

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