Current practice and future perspectives in the treatment of short bowel syndrome in children

• Verfasst von: Weih, Sandra [VerfasserIn]
• Verfasst von: Kessler, Markus [VerfasserIn]
• Verfasst von: Fonouni, Hamidreza [VerfasserIn]
• Verfasst von: Golriz, Mohammad [VerfasserIn]
• Verfasst von: Hafezi, Mohammadreza [VerfasserIn]
• Verfasst von: Mehrabi, Arianeb [VerfasserIn]
• Verfasst von: Holland-Cunz, Stefan [VerfasserIn]
• Titel: Current practice and future perspectives in the treatment of short bowel syndrome in children
• Titelzusatz: a systematic review
• Verf.angabe: S. Weih, M. Kessler, H. Fonouni, M. Golriz, M. Hafezi, A. Mehrabi, S. Holland-Cunz
• Jahr: 2012
• Jahr des Originals: 2011
• Umfang: 9 S.
• Fussnoten: First online: 22 November 2011 ; Gesehen am 06.05.2019
• Titel Quelle: Enthalten in: Langenbeck's archives of surgery
• Ort Quelle: Berlin : Springer, 1948
• Jahr Quelle: 2012
• Band/Heft Quelle: 397(2012), 7, Seite 1043-1051
• ISSN Quelle: 1435-2451
• DOI: doi:10.1007/s00423-011-0874-8
• Datenträger: Online-Ressource
• Sprache: eng
• Sach-SW: Children
• Sach-SW: Malabsorption
• Sach-SW: Short bowel syndrome
• Sach-SW: Surgical treatment
• Sach-SW: Tissue engineering
• K10plus-PPN: 1664599835

Abstract

PurposeShort bowel syndrome (SBS) is a malabsorption disorder of the intestine, which leads to an inadequate alimentary supply. A number of therapeutic approaches are already in use, but research advances may provide new options in the future. The purpose of this paper was to provide an overview of the established therapeutic approaches together with a discussion of the future perspectives in the treatment of patients with SBS. We review those studies dealing with the treatment of SBS patients and discuss both surgical and non-surgical approaches together with tissue engineering.MethodsA systemic review of Medline-cited studies dealing with current practice and future perspectives in the treatment of short bowel in children was performed.ResultsSurgical approaches, non-surgical approaches, and tissue engineering which was used in the treatment of SBS were analyzed. Among the surgical approaches, the bowel lengthening procedures and small bowel transplantation are prevalent. Stimulants are most important concerning non-surgical approaches. Tissue engineering seems to be more experimental and was also evaluated.ConclusionThe treatment of SBS patients remains very complex. It is eminent to find the best therapeutic option for each patient and to individualize and modify the different possible types of applied techniques frequently.