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Verfasst von:Rönsch, Henriette [VerfasserIn]   i
 Matterne, Uwe [VerfasserIn]   i
 Ofenloch, Robert [VerfasserIn]   i
 Weisshaar, Elke [VerfasserIn]   i
Titel:Which outcomes have been measured in hand eczema trials?
Titelzusatz:a systematic review
Verf.angabe:Henriette Rönsch, Christian Apfelbacher, Richard Brans, Uwe Matterne, Sonja Molin, Robert Ofenloch, Jart A.F. Oosterhaven, Marie L.A. Schuttelaar, Elke Weisshaar, Yik Weng Yew, Andrea Bauer
E-Jahr:2019
Jahr:[April 2019]
Umfang:7 S.
Illustrationen:Diagramme
Fussnoten:First published: 11 January 2019 ; Gesehen am 14.05.2019
Titel Quelle:Enthalten in: Contact dermatitis
Ort Quelle:Oxford [u.a.] : Wiley-Blackwell, 1975
Jahr Quelle:2019
Band/Heft Quelle:80(2019), 4, Seite 201-207
ISSN Quelle:1600-0536
Abstract:The considerable heterogeneity of outcomes and measurement instruments in hand eczema trials substantially limits the evidence synthesis concerning therapeutic and preventive interventions. Therefore, the Hand Eczema Core Outcome Set (HECOS) initiative is developing a core outcome set for future trials. The first objective was to identify outcomes that were measured in previous trials, to group them in domains, and to identify their measurement instruments. We conducted a systematic review of controlled and randomized controlled hand eczema trials published since 2000. Sixty-one eligible studies were identified. Each assessed one or more of 47 outcomes in the “skin” domain. Eighteen trials (30%) additionally focused on preventive behaviour in risk occupations. Quality of life was measured in 13 studies (21%). Thirty-two distinct named instruments were applied, but 223 measurements (62%) were conducted with unnamed instruments. Only 32 studies (52%) defined a primary outcome. Twenty-nine trials (48%) provided some information on adverse events, but none gave any references concerning relevant methods. Our review confirms the need to harmonize outcome measurements in hand eczema trials. The findings form the basis for a consensus process to generate a core outcome set to improve the explanatory power and comparability of future hand eczema studies.
DOI:doi:10.1111/cod.13212
URL:Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.

Volltext: https://doi.org/10.1111/cod.13212
 Volltext: https://onlinelibrary.wiley.com/doi/abs/10.1111/cod.13212
 DOI: https://doi.org/10.1111/cod.13212
Datenträger:Online-Ressource
Sprache:eng
Sach-SW:core outcome set
 CS-COUSIN
 hand dermatitis
 outcome measurement instruments
K10plus-PPN:1665449357
Verknüpfungen:→ Zeitschrift

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