| |  Online-Ressource |
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| Verfasst von: | Mughal, Tariq I. [VerfasserIn]  |
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| | Hehlmann, Rüdiger [VerfasserIn] |
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| | Saußele, Susanne [VerfasserIn] |
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| Titel: | Recent advances in the genomics and therapy of BCR/ABL1-positive and -negative chronic myeloproliferative neoplasms |
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| Verf.angabe: | Tariq I. Mughal, Jason Gotlib, Ruben Mesa, Steffen Koschmieder, H. Jean Khoury, Jorge E. Cortes, Tiziano Barbui, Rüdiger Hehlmann, Michael Mauro, Susanne Saussele, Jerald P. Radich, Richard A. Van Etten, Giuseppe Saglio, Srdnan Verstovek, Robert Peter Gale, Omar Abdel-Wahab |
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| E-Jahr: | 2018 |
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| Jahr: | 14 February 2018 |
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| Umfang: | 8 S. |
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| Fussnoten: | Gesehen am 27.05.2019 |
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| Titel Quelle: | Enthalten in: Leukemia research |
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| Ort Quelle: | Amsterdam [u.a.] : Elsevier Science, 1977 |
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| Jahr Quelle: | 2018 |
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| Band/Heft Quelle: | 67(2018), Seite 67-74 |
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| ISSN Quelle: | 1873-5835 |
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| Abstract: | This review is based on the presentations and deliberations at the 7th John Goldman Chronic Myeloid Leukemia (CML) and Myeloproliferative Neoplasms (MPN) Colloquium which took place in Estoril, Portugal on the 15th October 2017, and the 11th post-ASH International Workshop on CML and MPN which took place on the 6th-7th December 2016, immediately after the 58th American Society of Hematology Annual Meeting. Rather than present a resume of the proceedings, we have elected to address some of the topical translational research and clinically relevant topics in greater detail. We address recent updates in the genetics and epigenetics of MPN, the mechanisms of transformation by mutant calreticulin, advances in the biology and therapy of systemic mastocytosis, clinical updates on JAK2 inhibitors and other therapeutic approaches for patients with MPNs, cardiovascular toxicity related to tyrosine kinase inhibitors and the concept of treatment-free remission for patients with CML. |
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| DOI: | doi:10.1016/j.leukres.2018.02.008 |
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| URL: | Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.
Volltext: https://doi.org/10.1016/j.leukres.2018.02.008 |
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| | Volltext: http://www.sciencedirect.com/science/article/pii/S0145212618300432 |
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| | DOI: https://doi.org/10.1016/j.leukres.2018.02.008 |
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| Datenträger: | Online-Ressource |
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| Sprache: | eng |
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| Sach-SW: | CALR |
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| | Cardiotoxicity |
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| | CML |
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| | JAK2 inhibitors |
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| | Mastocytosis |
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| | MPN |
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| | TFR |
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| K10plus-PPN: | 1666322628 |
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| Verknüpfungen: | → Zeitschrift |
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Recent advances in the genomics and therapy of BCR/ABL1-positive and -negative chronic myeloproliferative neoplasms / Mughal, Tariq I. [VerfasserIn]; 14 February 2018 (Online-Ressource)
