Children of mentally III parents at risk evaluation (COMPARE)

• Verfasst von: Christiansen, Hanna [VerfasserIn]
• Verfasst von: Zietlow, Anna-Lena [VerfasserIn]
• Verfasst von: Krisam, Johannes [VerfasserIn]
• Verfasst von: Klose, Christina [VerfasserIn]
• Verfasst von: Kieser, Meinhard [VerfasserIn]
• Titel: Children of mentally III parents at risk evaluation (COMPARE)
• Titelzusatz: design and methods of a randomized controlled multicenter study - part I
• Verf.angabe: Hanna Christiansen, Corinna Reck, Anna-Lena Zietlow, Kathleen Otto, Ricarda Steinmayr, Linda Wirthwein, Sarah Weigelt, Rudolf Stark, David D. Ebert, Claudia Buntrock, Johannes Krisam, Christina Klose, Meinhard Kieser and Christina Schwenck
• E-Jahr: 2019
• Jahr: 26 March 2019
• Umfang: 12 S.
• Fussnoten: Gesehen am 28.05.2019
• Titel Quelle: Enthalten in: Frontiers in psychiatry
• Ort Quelle: Lausanne : Frontiers Research Foundation, 2007
• Jahr Quelle: 2019
• Band/Heft Quelle: Volume 10 (March 2019) Artikel-Nummer 128, Seite 1-12, 12 Seiten
• ISSN Quelle: 1664-0640
• DOI: doi:10.3389/fpsyt.2019.00128
• Datenträger: Online-Ressource
• Sprache: eng
• Sach-SW: Children of mentally ill parents
• Sach-SW: intervention
• Sach-SW: Mental Disorders
• Sach-SW: prevention
• Sach-SW: transgenerational transmission
• K10plus-PPN: 1666380598

Abstract

Objectives: Mental disorders are frequent, associated with disability-adjusted life years, societal and economic costs. Children of parents with a mental illness (COPMI) are at an increased risk to develop disorders themselves. The transgenerational transmission of mental disorders has been conceptualized in a model that takes parental and family factors, the social environment (i.e. school, work, social support), parent-child-interaction and possible child outcomes into account. The goal of the “Children of Mentally Ill Parents At Risk Evaluation” (COMPARE) study will thus be twofold: 1) to establish the efficacy and cost-effectivness of a high-quality randomized controlled trial (RCT) with the aim of interrupting the intergenerational transmission of mental disorders in COPMI; 2) to test the components of the trans-generational transmission model of mental disorders. Methods: To implement a randomized controlled trial (RCT: comparison of parental cognitive behavioural therapy/CBT with CBT + Positive Parenting Program) that is flanked by four add-on projects that apply behavioral, psychophysiological, and neuro-imaging methods to examine potential moderators and mediators of risk transmission (projects COMPARE-emotion/-interaction/-work/-school). COMPARE-emotion targets emotion processing and regulation and its impact on the transgenerational disorder transmission; COMPARE-interaction focuses especially on the impact of maternal comorbid diagnoses of depression and anxiety disorders and will concentrate on different pathways of the impact of maternal disorders on socio-emotional and cognitive infant development, such as parent-infant interaction and the infant's stress regulation skills. COMPARE-work analyzes the transmission of strains a person experiences in one area of life to another (i. e. from family to work; spill-over), and how stress and strain are transmitted between indivuduals (i. e. from parent to child; cross-over). COMPARE-school focuses on the psychosocial adjustment, school performance, and subjective well-being in COPMI compared to an adequate control group of healthy children. Results: This study protocol reports on the interdisciplinary approach of COMPARE testing the model of the transgenerational transmission of mental disorders. Conclusion: The combination of applied basic with clinical research will facilitate the examination of specific risk transmission mechanisms, promotion, dissemination and implementation of results into a highly important but largely neglected field.