Cognitive and neurophysiological markers of ADHD persistence and remission

• Verfasst von: Cheung, Celeste H. M. [VerfasserIn]
• Verfasst von: Brandeis, Daniel [VerfasserIn]
• Verfasst von: Banaschewski, Tobias [VerfasserIn]
• Titel: Cognitive and neurophysiological markers of ADHD persistence and remission
• Verf.angabe: Celeste H.M. Cheung, Fruhling Rijsdijk, Gráinne McLoughlin, Daniel Brandeis, Tobias Banaschewski, Philip Asherson and Jonna Kuntsi
• E-Jahr: 2016
• Jahr: June 2016
• Umfang: 8 S.
• Fussnoten: Gesehen am 17.06.2019
• Titel Quelle: Enthalten in: The British journal of psychiatry
• Ort Quelle: Cambridge : Cambridge University Press, 1963
• Jahr Quelle: 2016
• Band/Heft Quelle: 208(2016), 6, Seite 548-555
• ISSN Quelle: 1472-1465
• DOI: doi:10.1192/bjp.bp.114.145185
• Datenträger: Online-Ressource
• Sprache: eng
• K10plus-PPN: 1667501348

Abstract

Background - Attention-deficit hyperactivity disorder (ADHD) persists in around two-thirds of individuals in adolescence and early adulthood. Aims - To examine the cognitive and neurophysiological processes underlying the persistence or remission of ADHD. Method - Follow-up data were obtained from 110 young people with childhood ADHD and 169 controls on cognitive, electroencephalogram frequency, event-related potential (ERP) and actigraph movement measures after 6 years. Results - ADHD persisters differed from remitters on preparation-vigilance measures (contingent negative variation, delta activity, reaction time variability and omission errors), IQ and actigraph count, but not on executive control measures of inhibition or working memory (nogo-P3 amplitudes, commission errors and digit span backwards). Conclusions - Preparation-vigilance measures were markers of remission, improving concurrently with ADHD symptoms, whereas executive control measures were not sensitive to ADHD persistence/remission. For IQ, the present and previous results combined suggest a role in moderating ADHD outcome. These findings fit with previously identified aetiological separation of the cognitive impairments in ADHD. The strongest candidates for the development of non-pharmacological interventions involving cognitive training and neurofeedback are the preparation-vigilance processes that were markers of ADHD remission.