Changes in sexuality during ulipristal acetate treatment in women with symptomatic uterine fibroids

• Verfasst von: Tuschy, Benjamin [VerfasserIn]
• Verfasst von: Gabbert, Mirja [VerfasserIn]
• Verfasst von: Weiß, Christel [VerfasserIn]
• Verfasst von: Hornemann, Amadeus [VerfasserIn]
• Verfasst von: Wuhrer, Anne [VerfasserIn]
• Verfasst von: Sütterlin, Marc [VerfasserIn]
• Verfasst von: Berlit, Sebastian [VerfasserIn]
• Titel: Changes in sexuality during ulipristal acetate treatment in women with symptomatic uterine fibroids
• Verf.angabe: Benjamin Tuschy, Mirja Gabbert, Christel Weiss, Amadeus Hornemann, Anne Wuhrer, Marc Sütterlin, Sebastian Berlit
• E-Jahr: 2018
• Jahr: 12 June 2018
• Umfang: 5 S.
• Fussnoten: Gesehen am 17.06.2019
• Titel Quelle: Enthalten in: European journal of obstetrics & gynecology and reproductive biology
• Ort Quelle: Amsterdam [u.a.] : Elsevier Science, 1973
• Jahr Quelle: 2018
• Band/Heft Quelle: 228(2018), Seite 106-110
• ISSN Quelle: 1872-7654
• DOI: doi:10.1016/j.ejogrb.2018.06.027
• Datenträger: Online-Ressource
• Sprache: eng
• Sach-SW: Patient expectation
• Sach-SW: Sexuality
• Sach-SW: Ulipristal acetate
• Sach-SW: Uterine fibroid
• K10plus-PPN: 1667534327

Abstract

Objective - To evaluate changes in sexuality in women treated with Ulipristal acetate (UPA) due to symptomatic uterine fibroids. - Study design - A total of 102 women with symptomatic uterine fibroids undergoing conservative therapy with UPA were enrolled in this observational study. Sexuality was evaluated before and after a three month UPA treatment using the Female Sexual Functioning Index (FSFI) as well as the Sexual Activity Questionnaire (SAQ). Before treatment was initiated, participants additionally filled in a standardised questionnaire addressing the expected changes in sexuality due to UPA. Demographic parameters, expectations concerning changes in sexuality, and FSFI- and SAQ-scores were analysed. - Results - The average age of the study collective was 42.3 years. For the majority of the included women (n=70; 71.4%) sexuality was rated as an important issue and 86 women (87.8%) did not think that UPA would have an impact on the frequency of sexual intercourse, the quality (n=91; 92.9%) or frequency of orgasms (n=87; 88.8%) neither sexual receptivity (n=88; 89.8%). Full data sets were available for 73 patients (71.6%). The FSFI showed significantly higher sub scores regarding desire (3.6±1.2 vs. 3.9±1.2; p=0.0012) and arousal (4.2±1.7 vs. 4.4±1.9; p=0.0151) as well as a higher total score (26.6±9.0 vs. 27.4±9.5; p=0.0008) after UPA treatment. Regarding the SAQ a statistically significant difference regarding the subscore “habit” was found (p<0.0001) comparing pre with post interventional scores. - Conclusion - Sexuality in general seems to be important for women with symptomatic uterine fibroids. As the treatment with UPA appears to improve sexuality, this circumstance can be mentioned in a pre-therapeutic counselling.