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Verfasst von:Kehl, Sven [VerfasserIn]   i
 Schelkle, Anika Luise [VerfasserIn]   i
 Tuschy, Benjamin [VerfasserIn]   i
 Berlit, Sebastian [VerfasserIn]   i
 Weiß, Christel [VerfasserIn]   i
 Sütterlin, Marc [VerfasserIn]   i
Titel:Single deepest vertical pocket or amniotic fluid index as evaluation test for predicting adverse pregnancy outcome (SAFE trial)
Titelzusatz:a multicenter, open-label, randomized controlled trial
Verf.angabe:S. Kehl, A. Schelkle, A. Thomas, A. Puhl, K. Meqdad, B. Tuschy, S. Berlit, C. Weiss, C. Bayer, J. Heimrich, U. Dammer, E. Raabe, M. Winkler, F. Faschingbauer, M.W. Beckmann and M. Sütterlin
Jahr:2016
Jahr des Originals:2015
Umfang:6 S.
Fussnoten:Gesehen am 18.06.2019 ; First published: 10 June 2015
Titel Quelle:Enthalten in: Ultrasound in obstetrics & gynecology
Ort Quelle:New York, NY [u.a.] : Wiley, 1991
Jahr Quelle:2016
Band/Heft Quelle:47(2016), 6, Seite 674-679
ISSN Quelle:1469-0705
Abstract:Objective To determine whether the amniotic fluid index (AFI) or the single deepest vertical pocket (SDP) technique for estimating amniotic fluid volume is superior for predicting adverse pregnancy outcome. Methods This was a multicenter randomized controlled trial including 1052 pregnant women with a term singleton pregnancy across four hospitals in Germany. Women were assigned randomly, according to a computer-generated allocation sequence, to AFI or SDP measurement for estimation of amniotic fluid volume. Oligohydramnios was defined as AFI ≤ 5 cm or the absence of a pocket measuring at least 2 × 1 cm. The diagnosis of oligohydramnios was followed by labor induction. The primary outcome measure was postpartum admission to a neonatal intensive care unit. Further outcome parameters were the rates of diagnosis of oligohydramnios and induction of labor (for oligohydramnios or without specific indication), and mode of delivery. Results Postpartum admission to a neonatal intensive care unit was similar between groups (4.2% (n = 21) vs 5.0% (n = 25); relative risk (RR), 0.85 (95% CI, 0.48-1.50); P = 0.57). In the AFI group, there were more cases of oligohydramnios (9.8% (n = 49) vs 2.2% (n = 11); RR, 4.51 (95% CI, 2.2-8.57); P < 0.01) and more cases of labor induction for oligohydramnios (12.7% (n = 33) vs 3.6% (n = 10); RR, 3.50 (95% CI, 1.76-6.96); P < 0.01) than in the SDP group. Moreover, an abnormal cardiotocography was seen more often in the AFI group than in the SDP group (32.3% (n = 161) vs 26.2% (n = 132); RR, 1.23 (95% CI, 1.02-1.50); P = 0.03). The other outcome measures were not significantly different between the two groups. Conclusions Use of the AFI method increased the rate of diagnosis of oligohydramnios and labor induction for oligohydramnios without improving perinatal outcome. The SDP method is therefore the favorable method to estimate amniotic fluid volume, especially in a population with many low-risk pregnancies. Copyright © 2015 ISUOG. Published by John Wiley & Sons Ltd.
DOI:doi:10.1002/uog.14924
URL:Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.

Volltext: https://doi.org/10.1002/uog.14924
 Volltext: https://obgyn.onlinelibrary.wiley.com/doi/abs/10.1002/uog.14924
 DOI: https://doi.org/10.1002/uog.14924
Datenträger:Online-Ressource
Sprache:eng
Sach-SW:AFI
 amniotic fluid index
 amniotic fluid volume
 labor induction
 oligohydramnios
 perinatal outcome
 SDP
 single deepest pocket
K10plus-PPN:1667628836
Verknüpfungen:→ Zeitschrift

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