Optical coherence tomography angiography in retinal vein occlusions

• Verfasst von: Wang, Qian [VerfasserIn]
• Verfasst von: Jonas, Jost B. [VerfasserIn]
• Titel: Optical coherence tomography angiography in retinal vein occlusions
• Verf.angabe: Qian Wang, Szy Yann Chan, Yanni Yan, Jingyan Yang, Wenjia Zhou, Jost B. Jonas, Wen Bin Wei
• E-Jahr: 2018
• Jahr: 16 June 2018
• Umfang: 8 S.
• Fussnoten: Gesehen am 19.06.2019
• Titel Quelle: Enthalten in: Graefe's archive for clinical and experimental ophthalmology
• Ort Quelle: Berlin : Springer, 1854
• Jahr Quelle: 2018
• Band/Heft Quelle: 256(2018), 9, Seite 1615-1622
• ISSN Quelle: 1435-702X
• DOI: doi:10.1007/s00417-018-4038-1
• Datenträger: Online-Ressource
• Sprache: eng
• Sach-SW: Adolescent
• Sach-SW: Adult
• Sach-SW: Aged
• Sach-SW: Capillaries
• Sach-SW: Female
• Sach-SW: Fluorescein angiography
• Sach-SW: Fluorescein Angiography
• Sach-SW: Foveal avascular zone
• Sach-SW: Humans
• Sach-SW: Ischemia
• Sach-SW: Male
• Sach-SW: Middle Aged
• Sach-SW: Optical coherence tomography angiography
• Sach-SW: Prospective Studies
• Sach-SW: Retinal vein occlusion
• Sach-SW: Retinal Vein Occlusion
• Sach-SW: Retinal Vessels
• Sach-SW: Tomography, Optical Coherence
• Sach-SW: Young Adult
• K10plus-PPN: 1667638459

Abstract

PURPOSE: To examine the vascular density in different retinal layers and in the choriocapillaris in eyes with retinal vein occlusions (RVO). - METHODS: Applying optical coherence tomography angiography (OCTA), we examined patients with unilateral RVOs and normal individuals of a control group. - RESULTS: The study group included 48 patients with unilateral RVO and the control group 17 normal individuals. Eyes affected by RVO as compared to the contralateral unaffected eyes (all P < 0.001), and the contralateral unaffected eyes as compared to the eyes of the control group (P < 0.05), showed a lower vessel density in the superficial and deep retinal layers in all regions except for the foveal region. Choriocapillaris density was lower (P < 0.001), foveal retinal thickness and subfoveal choroidal thickness (P < 0.001) were thicker, and the foveal avascular zone was larger (P = 0.003) in the RVO eyes than in the contralateral eyes. For 29 eyes undergoing OCTA and fluorescein angiography, two examiners independently rated the retinas to be ischemic in fluorescein angiography in 14 eyes and in OCTA in 9 of these 14 eyes. - CONCLUSIONS: Upon OCTA, unaffected eyes of patients with unilateral RVOs showed vascular abnormalities in the superficial and deep retinal layers when compared to those of healthy individuals.