Online-Ressource | |
Verfasst von: | Rathmann, Nils-Andreas [VerfasserIn] |
Budjan, Johannes [VerfasserIn] | |
Attenberger, Ulrike [VerfasserIn] | |
Kostrzewa, Michael [VerfasserIn] | |
Sadick, Maliha [VerfasserIn] | |
Schönberg, Stefan [VerfasserIn] | |
Diehl, Steffen J. [VerfasserIn] | |
Titel: | Semiautomatic whole-lesion apparent diffusion coefficient assessment for early prediction of liver tumor response to radioembolization |
Verf.angabe: | Nils Rathmann, Johannes Budjan, Fatinah Mari, Robert Grimm, Ulrike Attenberger, Michael Kostrzewa, Maliha Sadick, Stefan O. Schoenberg and Steffen J. Diehl |
E-Jahr: | 2016 |
Jahr: | June 2016 |
Umfang: | 6 S. |
Fussnoten: | Gesehen am 25.06.2019 |
Titel Quelle: | Enthalten in: Anticancer research |
Ort Quelle: | Attiki, 2004 |
Jahr Quelle: | 2016 |
Band/Heft Quelle: | 36(2016), 6, Seite 2961-2966 |
ISSN Quelle: | 1791-7530 |
Abstract: | Aim: To evaluate volume-based apparent diffusion coefficient (ADCVOL) values for early prediction of therapy response after radioembolization (RE) of primary and secondary liver malignancies using a semiautomatic, image analysis software prototype. Patients and Methods: In a retrospective analysis, 74 target lesions were assessed in terms of therapy response 1 month after RE using magnetic resonance imaging. Changes of the diameter of the target lesions, the mean ADC value in a representative single-slice region of interest (ADCROI) and mean ADCVOL were correlated. Results: The median progression-free interval (PFI) of patients overall was 3.5±5.9 months. PFI in patients with an ADCVOL increase was statistically significantly longer than in patients with an ADCVOL decrease (mean PFI=6.5 vs. 2.5 months; p=0.0374). No correlation between PFI and early changes in lesion diameter or ADCROI was found. Conclusion: Semiautomatic, software-based ADC volume measurements seem to offer a clinically valuable parameter for early prediction of therapy response in patients after RE. |
URL: | Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt. Kostenfrei: Volltext ; Verlag ; Resolving-System: https://doi.org/undefined |
Kostenfrei: Volltext: http://ar.iiarjournals.org/content/36/6/2961 | |
Datenträger: | Online-Ressource |
Sprache: | eng |
Sach-SW: | apparent diffusion coefficient |
liver tumor | |
radioembolization | |
semiautomatic analysis | |
Volumetric measurement | |
K10plus-PPN: | 1667928538 |
Verknüpfungen: | → Zeitschrift |