Status: Bibliographieeintrag
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| Online-Ressource |
Verfasst von: | Grübler, Martin R. [VerfasserIn]  |
| März, Winfried [VerfasserIn]  |
Titel: | Effects of vitamin D supplementation on glycated haemoglobin and fasting glucose levels in hypertensive patients |
Titelzusatz: | a randomized controlled trial |
Verf.angabe: | M. R. Grübler, M. Gaksch, K. Kienreich, N. Verheyen, J. Schmid, B. ó Hartaigh, G. Richtig, H. Scharnagl, A. Meinitzer, A. Fahrleitner‐Pammer, W. März, A. Tomaschitz, S. Pilz |
E-Jahr: | 2016 |
Jahr: | 23 June 2016 |
Umfang: | 7 S. |
Fussnoten: | Gesehen am 09.07.2019 |
Titel Quelle: | Enthalten in: Diabetes, obesity and metabolism |
Ort Quelle: | Oxford [u.a.] : Wiley-Blackwell, 1999 |
Jahr Quelle: | 2016 |
Band/Heft Quelle: | 18(2016), 10, Seite 1006-1012 |
ISSN Quelle: | 1463-1326 |
Abstract: | Aim To investigate the efficacy of vitamin D supplementation on glycaemic control. Methods The Styrian Vitamin D Hypertension Trial was a single-centre, double-blind, placebo-controlled study conducted between 2011 and 2014 at the Medical University of Graz, Austria. We enrolled 200 people with arterial hypertension and 25-hydroxyvitamin D [25(OH)D] concentrations <30 ng/mL. Study participants were randomized to receive either 2800 IU of vitamin D or placebo per day for 8 weeks. The present study was a post hoc analysis that incorporated an analysis of covariance (ancova) approach, while adjusting for baseline differences. Results A total of 185 participants [mean ± standard deviation age, 60.1 ± 11.3 years; 47% women; mean 25(OH)D 21.2 ± 5.6 ng/mL, mean glycated haemoglobin (HbA1c) 44.8 ± 11.8 mmol/mol and mean body mass index 30.4 ± 5.4 kg/m2] completed the trial. ancova showed a mean treatment effect [95% confidence interval (CI)] on HbA1c of −3.52 (−6.7 to −0.34) mmol/mol (p = .045). There was no difference in fasting glucose −4.7 mg/dL (95% CI −16.3 to 6.9; p = .426). Conclusions Vitamin D supplementation in obese hypertensive patients with low 25(OH)D reduces HbA1c levels. This finding warrants further investigation into potential vitamin D effects on glucose homeostasis. |
DOI: | doi:10.1111/dom.12709 |
URL: | Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.
Volltext: https://doi.org/10.1111/dom.12709 |
| Volltext: https://onlinelibrary.wiley.com/doi/abs/10.1111/dom.12709 |
| DOI: https://doi.org/10.1111/dom.12709 |
Datenträger: | Online-Ressource |
Sprache: | eng |
Sach-SW: | cardiovascular disease |
| randomised trial |
| type 2 diabetes |
K10plus-PPN: | 1668807319 |
Verknüpfungen: | → Zeitschrift |
Effects of vitamin D supplementation on glycated haemoglobin and fasting glucose levels in hypertensive patients / Grübler, Martin R. [VerfasserIn]; 23 June 2016 (Online-Ressource)
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