Comparison of spoiled gradient echo and steady-state free-precession imaging for native myocardial T1 mapping using the slice-interleaved T1 mapping (STONE) sequence

• Verfasst von: Jang, Jihye [VerfasserIn]
• Verfasst von: Weingärtner, Sebastian [VerfasserIn]
• Titel: Comparison of spoiled gradient echo and steady-state free-precession imaging for native myocardial T1 mapping using the slice-interleaved T1 mapping (STONE) sequence
• Verf.angabe: Jihye Jang, Steven Bellm, Sébastien Roujol, Tamer A. Basha, Maryam Nezafat, Shingo Kato, Sebastian Weingärtner, Reza Nezafat
• E-Jahr: 2016
• Jahr: 23 September 2016
• Umfang: 11 S.
• Fussnoten: Gesehen am 09.07.2019
• Titel Quelle: Enthalten in: NMR in biomedicine
• Ort Quelle: New York, NY : Wiley, 1988
• Jahr Quelle: 2016
• Band/Heft Quelle: 29(2016), 10, Seite 1486-1496
• ISSN Quelle: 1099-1492
• DOI: doi:10.1002/nbm.3598
• Datenträger: Online-Ressource
• Sprache: eng
• Sach-SW: balanced steady-state free precession
• Sach-SW: cardiovascular MR (CMR) methods
• Sach-SW: myocardial T1 mapping
• Sach-SW: relaxometry
• Sach-SW: slice-interleaved T1 mapping
• Sach-SW: spoiled gradient echo
• K10plus-PPN: 166886228X

Abstract

Cardiac T1 mapping allows non-invasive imaging of interstitial diffuse fibrosis. Myocardial T1 is commonly calculated by voxel-wise fitting of the images acquired using balanced steady-state free precession (SSFP) after an inversion pulse. However, SSFP imaging is sensitive to B1 and B0 imperfection, which may result in additional artifacts. A gradient echo (GRE) imaging sequence has been used for myocardial T1 mapping; however, its use has been limited to higher magnetic field to compensate for the lower signal-to-noise ratio (SNR) of GRE versus SSFP imaging. A slice-interleaved T1 mapping (STONE) sequence with SSFP readout (STONE-SSFP) has been recently proposed for native myocardial T1 mapping, which allows longer recovery of magnetization (>8 R-R) after each inversion pulse. In this study, we hypothesize that a longer recovery allows higher SNR and enables native myocardial T1 mapping using STONE with GRE imaging readout (STONE-GRE) at 1.5T. Numerical simulations and phantom and in vivo imaging were performed to compare the performance of STONE-GRE and STONE-SSFP for native myocardial T1 mapping at 1.5T. In numerical simulations, STONE-SSFP shows sensitivity to both T2 and off resonance. Despite the insensitivity of GRE imaging to T2, STONE-GRE remains sensitive to T2 due to the dependence of the inversion pulse performance on T2. In the phantom study, STONE-GRE had inferior accuracy and precision and similar repeatability as compared with STONE-SSFP. In in vivo studies, STONE-GRE and STONE-SSFP had similar myocardial native T1 times, precisions, repeatabilities and subjective T1 map qualities. Despite the lower SNR of the GRE imaging readout compared with SSFP, STONE-GRE provides similar native myocardial T1 measurements, precision, repeatability, and subjective image quality when compared with STONE-SSFP at 1.5T.