Online-Ressource | |
Verfasst von: | Greulich, Simon [VerfasserIn] |
André, Florian [VerfasserIn] | |
Buß, Sebastian Johannes [VerfasserIn] | |
Katus, Hugo [VerfasserIn] | |
Titel: | Value of adenosine stress cardiovascular magnetic resonance in the evaluation of vessels supplying previously infarcted territories |
Verf.angabe: | Simon Greulich, Maik Backes, Hannah Steubing, Andreas Seitz, Maria Chatzitofi, Philipp Kaesemann, Florian Andre, Sebastian J. Buss, Hugo A. Katus, Heiko Mahrholdt |
E-Jahr: | 2019 |
Jahr: | 2019/05/01 |
Umfang: | 10 S. |
Fussnoten: | Gesehen am 10.07.2019 |
Titel Quelle: | Enthalten in: Coronary artery disease |
Ort Quelle: | London : Lippincott Williams & Wilkins, 1990 |
Jahr Quelle: | 2019 |
Band/Heft Quelle: | 30(2019), 3, Seite 222-231 |
ISSN Quelle: | 1473-5830 |
Abstract: | Background The diagnostic performance of adenosine stress cardiovascular magnetic resonance (CMR) for the detection of significant stenosis in infarct-related arteries is widely unknown. Two different types of perfusion defects can be observed: (a) larger than or (b) equal size as scar. - We hypothesized that: (a) defect>scar predicts significant coronary stenosis, and (b) defect=scar predicts an unobstructed infarct-related artery, and (c) angina symptoms might be of additional value in stratification. - Patients and methods Patients with previous myocardial infarction referred for work-up of myocardial ischemia undergoing adenosine stress CMR were included if they had coronary angiography within 4 weeks of CMR. - Results Two hundred patients with a mean age of 66±11 years, ischemic scars (subendocardial/transmural), and a mean left ventricular ejection fraction of 53% were included. In patients with defect>scar, the positive predictive value was excellent (88%) and typical angina was reported only in the stenosis group (P=0.002). However, patients with defect=scar (with 50% showing subendocardial scar) had a prevalence of 37% for stenosis, yielding a low negative predictive value of 63%. In this group, symptoms of typical angina were independent of stenosis (P=1.0). - Conclusion A perfusion defect larger than scar is highly predictive for significant stenosis in infarct-related arteries. However, more than a third of the patients with perfusion defect of equal size as scar also showed significant coronary stenosis. As half of these patients showed still viable (subendocardial) scars, there is a high-risk of reinfarction. The addition of angina symptoms seems to increase diagnostic accuracy only in patients with perfusion defects larger than scar. |
DOI: | doi:10.1097/MCA.0000000000000705 |
URL: | Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt. Volltext: https://doi.org/10.1097/MCA.0000000000000705 |
Volltext: https://journals.lww.com/coronary-artery/Abstract/2019/05000/Value_of_adenosine_stress_cardiovascular_magnetic.10.aspx | |
DOI: https://doi.org/10.1097/MCA.0000000000000705 | |
Datenträger: | Online-Ressource |
Sprache: | eng |
K10plus-PPN: | 166892398X |
Verknüpfungen: | → Zeitschrift |