Pseudo-diffusion effects in lung MRI

• Verfasst von: Ziener, Christian H. [VerfasserIn]
• Verfasst von: Kurz, Felix T. [VerfasserIn]
• Verfasst von: Schlemmer, Heinz-Peter [VerfasserIn]
• Verfasst von: Buschle, Lukas R. [VerfasserIn]
• Titel: Pseudo-diffusion effects in lung MRI
• Verf.angabe: C.H. Ziener, T. Kampf, F.T. Kurz, H.P. Schlemmer, L.R. Buschle
• Jahr: 2019
• Jahr des Originals: 2018
• Umfang: 11 S.
• Fussnoten: Available online 29 November 2018 ; Gesehen am 11.07.2019
• Titel Quelle: Enthalten in: Journal of magnetic resonance
• Ort Quelle: Amsterdam [u.a.] : Elsevier, 1969
• Jahr Quelle: 2019
• Band/Heft Quelle: 299(2019), Seite 1-11
• ISSN Quelle: 1096-0856
• DOI: doi:10.1016/j.jmr.2018.11.015
• Datenträger: Online-Ressource
• Sprache: eng
• Sach-SW: Bloch-Torrey-equation
• Sach-SW: Lung MRI
• Sach-SW: Pseudo-diffusion effects
• Sach-SW: Susceptibility effects
• K10plus-PPN: 1669007510

Abstract

Magnetic resonance imaging of lung tissue is strongly influenced by susceptibility effects between spin-bearing water molecules and air-filled alveoli. The measured lineshape, however, also depends on the interplay between susceptibility effects and blood-flow around alveoli that can be approximated as pseudo-diffusion. Both effects are quantitatively described by the Bloch-Torrey-equation, which was so far only solved for dephasing on the alveolar surface. In this work, we extend this model to the whole range of physiological relevant air volume fractions. The results agree very well with in vivo measurements in human lung tissue.