| |  Online-Ressource |
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| Verfasst von: | Budjan, Johannes [VerfasserIn]  |
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| | Lassel, Elke Angelika [VerfasserIn] |
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| | Pilz, Lothar R. [VerfasserIn] |
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| | Reichert, Miriam [VerfasserIn] |
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| | Rathmann, Nils-Andreas [VerfasserIn] |
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| | Diehl, Steffen J. [VerfasserIn] |
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| | Schönberg, Stefan [VerfasserIn] |
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| | Attenberger, Ulrike [VerfasserIn] |
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| Titel: | Semi-automatic volumetric measurement of treatment response in hepatocellular carcinoma after trans-arterial chemoembolization |
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| Verf.angabe: | Johannes Budjan, Elke A. Sauter, John N. Morelli, Marco Nolden, Andreas Fetzer, Lothar Pilz, Miriam Reichert, Theresa Brandt, Jan Hansmann, Stefan Haneder, Nils Rathmann, Steffen J. Diehl, Hans-Peter Meinzer, Stefan O. Schoenberg and Ulrike I. Attenberger |
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| E-Jahr: | 2016 |
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| Jahr: | August 2016 |
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| Umfang: | 6 S. |
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| Fussnoten: | Gesehen am 16.07.2019 |
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| Titel Quelle: | Enthalten in: Anticancer research |
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| Ort Quelle: | Kapandriti, Attiki, Greece : International Institute of Anticancer Research, 2004 |
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| Jahr Quelle: | 2016 |
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| Band/Heft Quelle: | 36(2016), 8, Seite 4353-4358 |
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| ISSN Quelle: | 1791-7530 |
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| Abstract: | Aim: To perform a quantitative, volumetric analysis of therapeutic effects of trans-arterial chemoembolization (TACE) in hepatocellular carcinoma (HCC) patients. Patients and Methods: Entire tumor volume and a subset of hypervascular tumor portions were analyzed pre- and post-TACE in magnetic resonance imaging datasets of 22 HCC patients using a semi-automated segmentation and evaluation tool from the Medical Imaging Interaction Toolkit. Results were compared to mRECIST measurements and inter-reader variability was assessed. Results: Mean total tumor volume increased statistical significantly after TACE (84.6 ml pre- vs. 97.1 ml post-TACE, p=0.03) while hypervascular tumor volume decreased from 9.1 ml pre- to 3.7 ml post-TACE (p=0.0001). Likewise, mRECIST diameters decreased significantly after therapy (44.2 vs. 15.4 mm). In the inter-reader assessment, overlap errors were 12.3-17.7% for entire and 36.3-64.2% for the enhancing tumor volume. Conclusion: Quantification of therapeutic changes after TACE therapy is feasible using a semi-automated segmentation and evaluation tool. Following TACE, hypervascular tumor volume decreases significantly. |
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| URL: | Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.
Volltext: https://doi.org/undefined |
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| | Volltext: http://ar.iiarjournals.org/content/36/8/4353 |
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| Datenträger: | Online-Ressource |
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| Sprache: | eng |
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| Sach-SW: | mRECIST |
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| | therapy assessment |
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| | Trans-arterial chemoembolization |
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| | volumetry |
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| K10plus-PPN: | 1669243249 |
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| Verknüpfungen: | → Zeitschrift |
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Semi-automatic volumetric measurement of treatment response in hepatocellular carcinoma after trans-arterial chemoembolization / Budjan, Johannes [VerfasserIn]; August 2016 (Online-Ressource)
