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Verfasst von:Frese, Cornelia [VerfasserIn]   i
 Krüger, Tanja [VerfasserIn]   i
 Staehle, Hans Jörg [VerfasserIn]   i
 Lux, Christopher J. [VerfasserIn]   i
 Erber, Ralf [VerfasserIn]   i
Titel:Biological evaluation of subgingivally placed direct resin composite materials
Verf.angabe:Cornelia Frese, Diana Wolff, Tanja Krüger, Hans J. Staehle, Christopher J. Lux, and Ralf Erber
E-Jahr:2018
Jahr:January 29, 2018
Umfang:8 S.
Fussnoten:Gesehen am 23.07.2019
Titel Quelle:Enthalten in: Journal of oral science
Ort Quelle:Tokyo : Nihon Univ. School of Dentistry, 2003
Jahr Quelle:2018
Band/Heft Quelle:60(2018), 1, Seite 89-96
ISSN Quelle:1880-4926
Abstract:Placement of composite resin restorations in deep subgingival cavities can damage surrounding soft tissues. In addition, commonly used resin-based composites (RBCs) might interfere with wound healing and periodontal health. To clarify cellular interactions with RBCs, we used an MTT assay to investigate adhesion of primary human gingival fibroblasts and human osteoblasts (hFOB 1.19) on five RBC materials with and without surface modifications (alumina blasting with 50- or 110-μm Al2O3). In addition, high-performance liquid chromatography (HPLC) was used to determine release of resin monomers from RBCs after 1 h, 1 day, and 7 days. As compared with tissue culture plastics (the control), cellular adhesion was significantly lower (P < 0.001) for human gingival fibroblasts and osteoblasts. Only minor, nonsignificant differences between individual RBCs were identified. HPLC analyses identified the release of three bifunctional methacrylates bisphenol A glycerolate dimethacrylate, triethylene glycol dimethacrylate, and diurethane dimethacrylate from RBCs and showed that monomer release increased between 1 h and 1 day but remained low. The present findings suggest that surface adhesion in the subgingival area is limited for the tested RBCs. Although residual monomer release was low for all tested RBCs, it might be sufficient to adversely affect cell adhesion.
DOI:doi:10.2334/josnusd.16-0827
URL:Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.

Volltext: https://doi.org/10.2334/josnusd.16-0827
 DOI: https://doi.org/10.2334/josnusd.16-0827
Datenträger:Online-Ressource
Sprache:eng
Sach-SW:biological assessment
 HPLC
 MTT assay
 subgingival composite restorations
K10plus-PPN:1669612538
Verknüpfungen:→ Zeitschrift

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