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Verfasst von:Sun, Huihui   i
 Liu, Bing [VerfasserIn]   i
 Cui, Jiaqu [VerfasserIn]   i
 Zhou, Zhao-Ming [VerfasserIn]   i
Titel:Survival analysis of patients with spinal chordomas
Verf.angabe:Hui-Hui Sun, Xin Hong, Bing Liu, Jia-Qu Cui, Zhao-Ming Zhou, Xin-Hui Xie, Xiao-Tao Wu
Jahr:2019
Jahr des Originals:2018
Umfang:8 S.
Fussnoten:Gesehen am 01.08.2019 ; Published online: 7 May 2018
Titel Quelle:Enthalten in: Neurosurgical review
Ort Quelle:Berlin : Springer, 1978
Jahr Quelle:2019
Band/Heft Quelle:42(2019), 2, Seite 455-462
ISSN Quelle:1437-2320
Abstract:This study was aimed to analyze the survival of patients with spinal chordomas. Patients’ data in the Surveillance, Epidemiology, and End Results (SEER) database were retrieved and analyzed statistically. There were 765 patients with spinal chordomas between 1974 and 2013. The overall survival did not improve significantly over decades for patients receiving surgery and radiotherapy (SR) (P = 0.221). There were significant differences in overall survival among subgroups of patients receiving surgery (S), radiotherapy (R), and neither S nor R (NSR) (P = 0.031, 0.037, and 0.031, respectively). Cancer-specific survival did not change significantly among subgroups of patients receiving R (P = 0.411), while it increased steadily among subgroups of patients receiving S, SR, and NSR (P < 0.001, 0.001, and 0.049, respectively). In the multivariate Cox regression model, younger onset age (hazard ratio [HR] 1.052, P < 0.001), surgery (HR 0.291, P = 0.001), and tumor location of the sacrum (HR 0.401, P = 0.002) were associated with a better overall survival. Similarly, younger onset age (HR 1.036, P = 0.029), surgery (HR 0.221, P = 0.009), and tumor location of the sacrum (HR 0.287, P = 0.002) were also associated with a higher cancer-specific survival. The changes in overall and cancer-specific survival over time differ among different treatment groups. Younger onset age, surgical strategy, and tumor location of the sacrum may be correlated with a higher overall and cancer-specific survival.
DOI:doi:10.1007/s10143-018-0968-7
URL:Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.

Volltext ; Verlag: https://doi.org/10.1007/s10143-018-0968-7
 Volltext: http://link.springer.com/10.1007/s10143-018-0968-7
 DOI: https://doi.org/10.1007/s10143-018-0968-7
Datenträger:Online-Ressource
Sprache:eng
K10plus-PPN:1670443264
Verknüpfungen:→ Zeitschrift

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