| Online-Ressource |
Verfasst von: | Diehl, Steffen J. [VerfasserIn]  |
| Rathmann, Nils-Andreas [VerfasserIn]  |
| Kostrzewa, Michael [VerfasserIn]  |
| Ritter, Manuel [VerfasserIn]  |
| Smakic, Arman [VerfasserIn]  |
| Schönberg, Stefan [VerfasserIn]  |
| Kriegmair, Maximilian [VerfasserIn]  |
Titel: | Irreversible electroporation for surgical renal masses in solitary kidneys |
Titelzusatz: | short-term interventional and functional outcome |
Verf.angabe: | Steffen J. Diehl, MD, Nils Rathmann, MD, Michael Kostrzewa, MD, Manuel Ritter, MD, Arman Smakic, MD, Stefan O. Schoenberg, MD, and Maximilian C. Kriegmair, MD |
E-Jahr: | 2016 |
Jahr: | September 2016 |
Umfang: | 7 S. |
Fussnoten: | Gesehen am 05.08.2019 ; Available online 9 June 2016 |
Titel Quelle: | Enthalten in: Journal of vascular and interventional radiology |
Ort Quelle: | Amsterdam [u.a.] : Elsevier, 1990 |
Jahr Quelle: | 2016 |
Band/Heft Quelle: | 27(2016), 9, Seite 1407-1413 |
ISSN Quelle: | 1535-7732 |
Abstract: | Purpose - To examine short-term outcomes and complications in patients with a solitary kidney treated with irreversible electroporation (IRE) for a potentially malignant renal mass. - Materials and Methods - Five patients (2 female, 3 male; mean age, 66 y) with 7 lesions who underwent IRE for renal tumors in a solitary kidney between August 2014 and August 2015 were retrospectively reviewed. Changes in signal intensity (SI) of the treated lesion were evaluated on contrast-enhanced magnetic resonance imaging. To evaluate functional outcome, creatinine levels and estimated glomerular filtration rate (eGFR) were compared vs baseline after 1 day, 2-7 days, 3-6 weeks, and 6-12 weeks after the intervention. - Results - Mean tumor diameter was 24.4 mm (range, 15-38 mm), with an average score of 7.7 (range, 4-9) per R.E.N.A.L. criteria (radius, exophytic/endophytic, nearness to collecting system or sinus, anterior/posterior, and location relative to polar lines). There was a progressive, significant decrease in treated tumor SI on follow-up imaging (mean, 70%-82%), suggesting a treatment response rate of 100% at a mean follow-up of 6.4 months (range, 3-11 mo). Two minor acute complications (Society of Interventional Radiology class A) occurred: transient gross hematuria and stage I acute kidney failure. Overall, there was no significant decrease in eGFR (−2.75 mL/min) over 3 months, even though 1 patient’s eGFR decreased from > 60 mL/min/1.73m2 to 44 mL/min/1.73m2. - Conclusions - The data suggest that percutaneous IRE for renal mass in patients with a solitary kidney is safe and feasible. It may help to preserve renal function and offers promising short-term oncologic results. |
DOI: | doi:10.1016/j.jvir.2016.03.044 |
URL: | Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.
Volltext: https://doi.org/10.1016/j.jvir.2016.03.044 |
| Volltext: http://www.sciencedirect.com/science/article/pii/S1051044316300227 |
| DOI: https://doi.org/10.1016/j.jvir.2016.03.044 |
Datenträger: | Online-Ressource |
Sprache: | eng |
K10plus-PPN: | 167056648X |
Verknüpfungen: | → Zeitschrift |
Irreversible electroporation for surgical renal masses in solitary kidneys / Diehl, Steffen J. [VerfasserIn]; September 2016 (Online-Ressource)