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Verfasst von:Kallenberger, Stefan M. [VerfasserIn]   i
 Schmid, Christian David [VerfasserIn]   i
 Wiedmann, Felix Tobias [VerfasserIn]   i
 Mereles, Derliz [VerfasserIn]   i
 Katus, Hugo [VerfasserIn]   i
 Thomas, Dierk [VerfasserIn]   i
 Schmidt, Constanze [VerfasserIn]   i
Titel:A simple, non-invasive score to predict paroxysmal atrial fibrillation
Verf.angabe:Stefan M. Kallenberger, Christian Schmid, Felix Wiedmann, Derliz Mereles, Hugo A. Katus, Dierk Thomas, Constanze Schmidt
E-Jahr:2016
Jahr:September 28, 2016
Umfang:16 S.
Fussnoten:Gesehen am 07.08.2019
Titel Quelle:Enthalten in: PLOS ONE
Ort Quelle:San Francisco, California, US : PLOS, 2006
Jahr Quelle:2016
Band/Heft Quelle:11(2016,9) Artikel-Nummer e0163621, 16 Seiten
ISSN Quelle:1932-6203
Abstract:Paroxysmal atrial fibrillation (pAF) is a major risk factor for stroke but remains often unobserved. To predict the presence of pAF, we developed model scores based on echocardiographic and other clinical parameters from routine cardiac assessment. The scores can be easily implemented to clinical practice and might improve the early detection of pAF. In total, 47 echocardiographic and other clinical parameters were collected from 1000 patients with sinus rhythm (SR; n = 728), pAF (n = 161) and cAF (n = 111). We developed logistic models for classifying between pAF and SR that were reduced to the most predictive parameters. To facilitate clinical implementation, linear scores were derived. To study the pathophysiological progression to cAF, we analogously developed models for cAF prediction. For classification between pAF and SR, amongst 12 selected model parameters, the most predictive variables were tissue Doppler imaging velocity during atrial contraction (TDI, A’), left atrial diameter, age and aortic root diameter. Models for classifying between pAF and SR or between cAF and SR showed areas under the ROC curves of 0.80 or 0.93, which resembles classifiers with high discriminative power. The novel risk scores were suitable to predict the presence of pAF based on variables readily available from routine cardiac assessment. Modelling helped to quantitatively characterize the pathophysiologic transition from SR via pAF to cAF. Applying the scores may improve the early detection of pAF and might be used as decision aid for initiating preventive interventions to reduce AF-associated complications.
DOI:doi:10.1371/journal.pone.0163621
URL:Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.

Volltext ; Verlag: https://doi.org/10.1371/journal.pone.0163621
 Volltext: https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0163621
 DOI: https://doi.org/10.1371/journal.pone.0163621
Datenträger:Online-Ressource
Sprache:eng
Sach-SW:Atrial fibrillation
 Cardiac atria
 Cardiology
 Catheters
 Coronary heart disease
 Doppler imaging
 Echocardiography
 Sleep apnea
K10plus-PPN:167072347X
Verknüpfungen:→ Zeitschrift

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