| Online-Ressource |
Verfasst von: | Eisenacher, Sarah [VerfasserIn]  |
| Rausch, Franziska [VerfasserIn]  |
| Englisch, Susanne Angelika [VerfasserIn]  |
| Becker, Anna [VerfasserIn]  |
| Mier, Daniela [VerfasserIn]  |
| Fenske, Sabrina C. [VerfasserIn]  |
| Meyer-Lindenberg, Andreas [VerfasserIn]  |
| Kirsch, Peter [VerfasserIn]  |
| Zink, Mathias [VerfasserIn]  |
Titel: | Early cognitive basic symptoms are accompanied by neurocognitive impairment in patients with an ‘at-risk mental state’ for psychosis |
Verf.angabe: | Sarah Eisenacher, Franziska Rausch, Fabian Ainser, Susanne Englisch, Anna Becker, Daniela Mier, Sabrina Fenske, Andreas Meyer‐Lindenberg, Peter Kirsch, Mathias Zink |
E-Jahr: | 2018 |
Jahr: | 12 May 2016 |
Umfang: | 10 S. |
Fussnoten: | Gesehen am 09.08.2019 |
Titel Quelle: | Enthalten in: Early intervention in psychiatry |
Ort Quelle: | Oxford [u.a.] : Wiley-Blackwell, 2007 |
Jahr Quelle: | 2018 |
Band/Heft Quelle: | 12(2018), 4, Seite 586-595 |
ISSN Quelle: | 1751-7893 |
Abstract: | Aim Patients with an increased risk for psychosis (‘at-risk mental state’ (ARMS)) present various neurocognitive deficits. Not least because of differences in identifying the ARMS, results of previous studies are inconsistent. In most studies ARMS-patients are classified by the experience of attenuated psychotic symptoms (APS) and/or brief limited intermittent psychotic symptoms (BLIPS). Few studies additionally assessed cognitive basic symptoms (BS). A comprehensive assessment in the very early stage of the ARMS is missing. Methods In the present study we characterized ARMS-patients for cognitive BS (ARMS-BS), APS and BLIPS (ARMS-A/B) according to the Early Recognition Inventory based on IRAOS (ERIraos). Furthermore, we assessed neurocognitive deficits using the MATRICS consensus cognitive battery for schizophrenia with a primary hypothesis regarding working memory performance. Groups of 38 ARMS-patients and 38 healthy controls were matched for age, gender, education and premorbid verbal intelligence. Results Between-group comparisons revealed significant poorer working memory performance in addition to lower verbal learning and problem solving, slower processing speed and lower global neurocognitive functioning in ARMS-patients as compared to controls. ARMS-BS did not differ from ARMS-A/B. Conclusions These results underscore the presence of cognitive limitations in patients only presenting with cognitive BS. Knowledge of these early cognitive deviations supports the inclusion of early ARMS-stages into a comprehensive concept of the psychosis risk state. Therapeutic interventions already applied at this stage might prevent deterioration of constraints. Longitudinal and interventional studies investigating the interaction of cognitive BS and neurocognitive as well as metacognitive deficits are warranted. |
DOI: | doi:10.1111/eip.12350 |
URL: | Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.
Volltext: https://doi.org/10.1111/eip.12350 |
| Volltext: https://onlinelibrary.wiley.com/doi/abs/10.1111/eip.12350 |
| DOI: https://doi.org/10.1111/eip.12350 |
Datenträger: | Online-Ressource |
Sprache: | eng |
Sach-SW: | at-risk mental state |
| cognition |
| ERIraos |
| prodrome |
| working memory |
K10plus-PPN: | 1671053311 |
Verknüpfungen: | → Zeitschrift |
Early cognitive basic symptoms are accompanied by neurocognitive impairment in patients with an ‘at-risk mental state’ for psychosis / Eisenacher, Sarah [VerfasserIn]; 12 May 2016 (Online-Ressource)