| |  Online-Ressource |
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| Verfasst von: | Schäfer, Mark [VerfasserIn]  |
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| | Gotthardt, Daniel [VerfasserIn] |
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| | Ganion, Nicole [VerfasserIn] |
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| | Wohnsland, Sascha [VerfasserIn] |
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| | Seeßle, Jessica [VerfasserIn] |
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| | Stremmel, Wolfgang [VerfasserIn] |
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| | Pfeiffenberger, Jan [VerfasserIn] |
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| | Weiss, Karl Heinz [VerfasserIn] |
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| Titel: | Wilson disease |
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| Titelzusatz: | health-related quality of life and risk for depression |
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| Verf.angabe: | Mark Schaefer, Daniel Nils Gotthardt, Nicole Ganion, Sascha Wohnsland, Jessica Seessle, Wolfgang Stremmel, Jan Pfeiffenberger, Karl Heinz Weiss |
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| Jahr: | 2016 |
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| Jahr des Originals: | 2015 |
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| Umfang: | 8 S. |
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| Fussnoten: | Available online 6 November 2015 ; Gesehen am 12.08.2019 |
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| Titel Quelle: | Enthalten in: Clinics and research in hepatology and gastroenterology |
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| Ort Quelle: | Amsterdam : Elsevier Masson, 2011 |
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| Jahr Quelle: | 2016 |
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| Band/Heft Quelle: | 40(2016), 3, Seite 349-356 |
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| ISSN Quelle: | 2210-741X |
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| Abstract: | Summary - Background - Wilson disease is an autosomal recessive disorder of copper metabolism and requires lifelong medical treatment. Therefore, the analysis of quality of life has gathered more attention. Aims of this study were to examine risk for depression and health-related quality of life in patients suffering from Wilson disease. - Methods - Sixty-eight patients were included in this retrospective cross sectional study. The Personal Health Questionnaire-9 Depression Scale was used to assess depression. The Short Form-36 Health Survey questionnaire was used to assess health-related quality of life. - Results - The Personal Health Questionnaire-9 indicated that 21% (14/68) of patients were at risk for major depressive disorders (scores>10) and 35% (24/68) were at risk for mild depression (scores 5-9). Women had significantly lower life quality scores than men. Primary neurologic disease manifestation was associated with significantly lower total Short Form-36 and subdimension scores compared with primary hepatic or mixed presentation. Overall, patients with Wilson disease experienced higher quality of life than patients with other chronic liver diseases. - Conclusions - As patients with Wilson disease have a high risk for depressive disorders, active assessment for depression is mandatory. Patients with primary neurological symptoms are at higher risk for reduction of life quality. |
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| DOI: | doi:10.1016/j.clinre.2015.09.007 |
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| URL: | Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.
Volltext ; Verlag: https://doi.org/10.1016/j.clinre.2015.09.007 |
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| | Volltext: http://www.sciencedirect.com/science/article/pii/S221074011500251X |
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| | DOI: https://doi.org/10.1016/j.clinre.2015.09.007 |
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| Datenträger: | Online-Ressource |
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| Sprache: | eng |
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| K10plus-PPN: | 1671228154 |
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| Verknüpfungen: | → Zeitschrift |
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