Status: Bibliographieeintrag
Standort: ---
Exemplare:
---
| |  Online-Ressource |
|---|
| Verfasst von: | Hallée, Stéphanie [VerfasserIn]  |
|---|
| | Kehrer, Jessica [VerfasserIn] |
|---|
| | Frischknecht, Friedrich [VerfasserIn] |
|---|
| | Mair, Gunnar R. [VerfasserIn] |
|---|
| Titel: | Identification of a Golgi apparatus protein complex important for the asexual erythrocytic cycle of the malaria parasite Plasmodium falciparum |
|---|
| Verf.angabe: | Stéphanie Hallée, Catherine Thériault, Dominic Gagnon, Jessica Kehrer, Friedrich Frischknecht, Gunnar R. Mair, Dave Richard |
|---|
| E-Jahr: | 2018 |
|---|
| Jahr: | 26 March 2018 |
|---|
| Umfang: | 13 S. |
|---|
| Fussnoten: | Gesehen am 21.08.2019 |
|---|
| Titel Quelle: | Enthalten in: Cellular microbiology |
|---|
| Ort Quelle: | London : Hindawi Limited, 1999 |
|---|
| Jahr Quelle: | 2018 |
|---|
| Band/Heft Quelle: | 20(2018,8) Artikel-Nummer e12843, 13 Seiten |
|---|
| ISSN Quelle: | 1462-5822 |
|---|
| Abstract: | Compared with other eukaryotic cell types, malaria parasites appear to possess a more rudimentary Golgi apparatus being composed of dispersed, unstacked cis and trans-cisternae. Despite playing a central role in the secretory pathway of the parasite, few Plasmodium Golgi resident proteins have been characterised. We had previously identified a new Golgi resident protein of unknown function, which we had named Golgi Protein 1, and now show that it forms a complex with a previously uncharacterised transmembrane protein (Golgi Protein 2, GP2). The Golgi Protein complex localises to the cis-Golgi throughout the erythrocytic cycle and potentially also during the mosquito stages. Analysis of parasite strains where GP1 expression is conditionally repressed and/or the GP2 gene is inactivated reveals that though the Golgi protein complex is not essential at any stage of the parasite life cycle, it is important for optimal asexual development in the blood stages. |
|---|
| DOI: | doi:10.1111/cmi.12843 |
|---|
| URL: | Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.
Volltext: https://doi.org/10.1111/cmi.12843 |
|---|
| | Volltext: https://onlinelibrary.wiley.com/doi/abs/10.1111/cmi.12843 |
|---|
| | DOI: https://doi.org/10.1111/cmi.12843 |
|---|
| Datenträger: | Online-Ressource |
|---|
| Sprache: | eng |
|---|
| Sach-SW: | gene knock out |
|---|
| | Golgi apparatus |
|---|
| | malaria |
|---|
| | Plasmodium |
|---|
| | protein complex |
|---|
| K10plus-PPN: | 1671731654 |
|---|
| Verknüpfungen: | → Zeitschrift |
|---|
Identification of a Golgi apparatus protein complex important for the asexual erythrocytic cycle of the malaria parasite Plasmodium falciparum / Hallée, Stéphanie [VerfasserIn]; 26 March 2018 (Online-Ressource)
68422690
