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Verfasst von:Antony, Pia-Anita [VerfasserIn]   i
 Harnoß, Julian-Camill [VerfasserIn]   i
 Schneider, Martin [VerfasserIn]   i
Titel:Urgent surgery in colon cancer has no impact on survival
Verf.angabe:Pia Antony, Julian C. Harnoss, Rene Warschkow, Bruno M. Schmied, Martin Schneider, Ignazio Tarantino, Alexis Ulrich
Jahr:2019
Umfang:9 S.
Fussnoten:Gesehen am 23.09.2019
Titel Quelle:Enthalten in: Journal of surgical oncology
Ort Quelle:Bognor Regis [u.a.] : Wiley, 1996
Jahr Quelle:2019
Band/Heft Quelle:119(2019), 8, Seite 1170-1178
ISSN Quelle:1096-9098
Abstract:Background and objectives Despite advances in early detection of colon cancer, a minority of patients still require urgent surgery. Whether such urgent conditions result in poor outcome remains a topic of debate. Methods Using a prospectively maintained database, patients suffering exclusively from colon cancer and receiving either elective or emergent resection between 2001 and 2014 were analyzed with respect to overall, disease-specific, and relative survival using Cox regression and propensity score analyses. Results From a total of 877 patients analyzed, 2.7% (24) presented with complications requiring urgent surgery. Propensity-scoring identified strongly biased patient characteristics (0.097 ± 0.069 vs 0.028 ± 0.043; P < 0.001). An unadjusted Cox proportional hazards regression analysis revealed urgent surgery as a statistically significant prognostic factor with an approximately 207% increased risk of mortality (hazard ratio [HR] = 3.07; 95% confidence interval [CI]: 1.62-5.81; P = 0.003). After adjusting the data according to the propensity score analysis, urgent surgery was not associated with a decreased overall (HR = 1.67; 95%CI; 0.84-3.36; P = 0.174), disease-specific (HR = 1.62; 95% CI; 0.81-3.24; P = 0.201) or relative survival (HR = 1.86; 95% CI: 0.92-3.79; P = 0.086). Conclusions After risk-adjustment, using multivariable Cox regression and propensity score analyses, no significant disadvantage could be noted with regard to overall, disease-specific, or relative survival in patients with exclusively colon cancer who received emergent oncological resection.
DOI:doi:10.1002/jso.25469
URL:Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.

Volltext ; Verlag: https://doi.org/10.1002/jso.25469
 Volltext: https://onlinelibrary.wiley.com/doi/abs/10.1002/jso.25469
 DOI: https://doi.org/10.1002/jso.25469
Datenträger:Online-Ressource
Sprache:eng
Sach-SW:colon cancer
 emergency
 surgery
 survival
 urgent
K10plus-PPN:1677536586
Verknüpfungen:→ Zeitschrift

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