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Verfasst von:Seker, Fatih [VerfasserIn]   i
 Pfaff, Johannes [VerfasserIn]   i
 Schönenberger, Silvia [VerfasserIn]   i
 Herweh, Christian [VerfasserIn]   i
 Nagel, Simon [VerfasserIn]   i
 Ringleb, Peter A. [VerfasserIn]   i
 Bendszus, Martin [VerfasserIn]   i
 Möhlenbruch, Markus Alfred [VerfasserIn]   i
Titel:Clinical outcome after thrombectomy in patients with stroke with premorbid modified rankin scale scores of 3 and 4
Titelzusatz:a cohort study with 136 patients
Verf.angabe:F. Seker, J. Pfaff, S. Schönenberger, C. Herweh, S. Nagel, P.A. Ringleb, M. Bendszus, and M.A. Möhlenbruch
E-Jahr:2019
Jahr:February 13, 2019
Umfang:4 S.
Fussnoten:Gesehen am 29.11.2019
Titel Quelle:Enthalten in: American journal of neuroradiology
Ort Quelle:Oak Brook, Ill. : Soc., 1980
Jahr Quelle:2019
Band/Heft Quelle:40(2019), 2, Seite 283-286
ISSN Quelle:1936-959X
Abstract:BACKGROUND AND PURPOSE: We aimed to analyze the clinical outcome after mechanical thrombectomy in patients with premorbid mRS 3 and 4 because there are currently no data on this patient group. - MATERIALS AND METHODS: Between January 2009 and November 2017, all patients with premorbid mRS 3 or 4 undergoing mechanical thrombectomy due to anterior circulation stroke were selected. Good outcome was defined as a clinical recovery to the status before stroke onset (ie, equal premorbid mRS and mRS at 90 days). In addition, mortality at discharge and at 90 days was analyzed. - RESULTS: One hundred thirty-six patients were included, of whom 81.6% presented with premorbid mRS 3; and 18.4%, with premorbid mRS 4; 24.0% of patients with premorbid mRS 4 achieved clinical recovery compared with 20.7% of patients with premorbid mRS 3 (P = .788). However, the proportion of hospital mortality and mortality at 90 days was nonsignificant, but markedly higher in patients with premorbid mRS 4. Multivariate analysis identified low NIHSS scores (OR, 0.92; 95% CI, 0.85-0.99; P = .040), high ASPECTS (OR, 1.45; 95% CI, 1.02-2.16; P = .049), and TICI 2b-3 (OR, 7.11; 95% CI, 1.73-49.90; P = .017) as independent predictors of good outcome. - CONCLUSIONS: Good outcome in patients with premorbid mRS 3 and 4 is less frequent compared with premorbid mRS 0-2. Nevertheless, about 20% of the patients return to their premorbid mRS, which may justify endovascular treatment. The most important predictor of good outcome is successful recanalization.
DOI:doi:10.3174/ajnr.A5920
URL:Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.

Volltext ; Verlag: https://doi.org/10.3174/ajnr.A5920
 Volltext: http://www.ajnr.org/content/40/2/283
 DOI: https://doi.org/10.3174/ajnr.A5920
Datenträger:Online-Ressource
Sprache:eng
K10plus-PPN:167755231X
Verknüpfungen:→ Zeitschrift

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