Menstrual cycle-related fluctuations in oxytocin concentrations

• Verfasst von: Engel, Sinha [VerfasserIn]
• Verfasst von: Ditzen, Beate [VerfasserIn]
• Titel: Menstrual cycle-related fluctuations in oxytocin concentrations
• Titelzusatz: a systematic review and meta-analysis
• Verf.angabe: Sinha Engel, Hannah Klusmann, Beate Ditzen, Christine Knaevelsrud, Sarah Schumacher
• Jahr: 2019
• Jahr des Originals: 2018
• Umfang: 12 S.
• Fussnoten: Available online 17 November 2018 ; Gesehen am 09.10.2019
• Titel Quelle: Enthalten in: Frontiers in neuroendocrinology
• Ort Quelle: Orlando, Fla. : Academic Press, 1993
• Jahr Quelle: 2019
• Band/Heft Quelle: 52(2019), Seite 144-155
• ISSN Quelle: 1095-6808
• DOI: doi:10.1016/j.yfrne.2018.11.002
• Datenträger: Online-Ressource
• Sprache: eng
• Sach-SW: Estradiol
• Sach-SW: Estrogens
• Sach-SW: Female
• Sach-SW: FSH
• Sach-SW: GnRH
• Sach-SW: LH
• Sach-SW: Menstrual cycle
• Sach-SW: Oxytocin
• Sach-SW: Progesterone
• K10plus-PPN: 1678546321

Abstract

Oxytocin affects physiological and psychological functions that are often expressed sex-specifically, suggesting interactions between oxytocin and sex hormones. As female sex hormone concentrations change during the menstrual cycle, oxytocin might fluctuate, too. This systematic review and meta-analysis investigated endogenous oxytocin concentrations across menstrual cycle phases in healthy women. Data from 13 studies (120 women) showed a significant increase of oxytocin concentrations from the early follicular phase to ovulation (g=0.39 [0.25; 0.53], p<.001) and a significant decrease from ovulation to the mid-luteal phase (g=−0.50 [−0.81; −0.18], p<.001). There were no significant differences between the early follicular and mid-luteal phase (g=−0.19 [−0.70; −0.32], p=.471). These findings contribute to a deeper understanding of differences in normal and abnormal psychobiological processes in women. They highlight the necessity to consider the menstrual cycle phase in studies on oxytocin in women.