Dimensions of the ciliary muscles of Brücke, Müller and Iwanoff and their associations with axial length and glaucoma

• Verfasst von: Mao, Ying [VerfasserIn]
• Verfasst von: Bai, Hai Xia [VerfasserIn]
• Verfasst von: Li, Bin [VerfasserIn]
• Verfasst von: Xu, Xiao Lin [VerfasserIn]
• Verfasst von: Gao, Fei [VerfasserIn]
• Verfasst von: Zhang, Zhi Bao [VerfasserIn]
• Verfasst von: Jonas, Jost B. [VerfasserIn]
• Titel: Dimensions of the ciliary muscles of Brücke, Müller and Iwanoff and their associations with axial length and glaucoma
• Verf.angabe: Ying Mao, Hai Xia Bai, Bin Li, Xiao Lin Xu, Fei Gao, Zhi Bao Zhang, Jost B. Jonas
• E-Jahr: 2018
• Jahr: [November 2018]
• Umfang: 7 S.
• Fussnoten: Gesehen am 11.10.2019
• Titel Quelle: Enthalten in: Graefe's archive for clinical and experimental ophthalmology
• Ort Quelle: Berlin : Springer, 1854
• Jahr Quelle: 2018
• Band/Heft Quelle: 256(2018), 11, Seite 2165-2171
• ISSN Quelle: 1435-702X
• DOI: doi:10.1007/s00417-018-4085-7
• Datenträger: Online-Ressource
• Sprache: eng
• Sach-SW: Bruch’s membrane
• Sach-SW: Brücke’s muscle
• Sach-SW: Ciliary muscle
• Sach-SW: Glaucoma
• Sach-SW: Intraocular pressure
• Sach-SW: Iwanoff’s muscle
• Sach-SW: Müller’s muscle
• Sach-SW: Scleral spur
• K10plus-PPN: 1678773506

Abstract

BackgroundTo assess the dimensions of Brücke’s muscle, as the longitudinal portion, and of Müller’s muscle and Iwanoff’s muscle combined as circular and radial/reticular portions of the ciliary muscle.MethodsThe histomorphometric study included human globes that had been enucleated due to an ocular tumor or end-stage glaucoma. After immunohistochemical staining of the ciliary muscles, the histology slides were examined under a light microscope applying a digitized image analysis system.ResultsThe study included 55 globes [axial length 25.6 ± 3.0 mm (range 21.0 mm-36.0 mm)] from 55 patients [mean age, 33.7 ± 18.3 years (range:1-66 years)]. Length of Brücke’s muscle (mean 3.40 ± 0.76 mm) increased with longer axial length (P < 0.001; regression coefficient beta: 0.52) and was not significantly associated with age (P = 0.12), presence of glaucoma (P = 0.11) or Brücke’s muscle thickness at the scleral spur (P = 0.32), at the site of the maximum thickness of the ciliary body (P = 0.84) or at the posterior end of Müller’s/Iwanoff’s muscle (P = 0.66), or with thickness (P = 0.29) and cross-sectional area (P = 0.85) of Müller’s/Iwanoff’s muscle. Mean distance between Brücke’s muscle end and the ora serrata measured 1.73 ± 1.13 mm and increased with longer axial length (P < 0.001; beta: 0.46). Distance from the scleral spur to the ora serrata (mean: 4.94 ± 1.42 mm; range: 3.08-9.09 mm) increased with longer axial length (P < 0.001; beta: 0.61). Maximal thickness (mean: 245 ± 125 μm) and cross-section area (mean: 0.19 ± 0.11 mm2) of Müller’s/Iwanoff’s muscle decreased significantly with the diagnosis of glaucoma (P = 0.02;beta:-0.38) and longer axial length (P = 0.03; beta: -0.35).ConclusionsLength of Brücke’s muscle increased with axial length of the globe, while its cross-sectional area was independent of axial length. Müller’s/Iwanoff’s muscle decreased in cross-sectional area with longer axis, and in particular with the presence of glaucoma, while the dimensions of Brücke’s muscle were not related to glaucoma.