| Online-Ressource |
Verfasst von: | Akbaba, Sati [VerfasserIn]  |
| Uzun-Lang, Kristin [VerfasserIn]  |
| Bulut, Cem [VerfasserIn]  |
| Held, Thomas [VerfasserIn]  |
| Rieken, Stefan [VerfasserIn]  |
| Plinkert, Peter K. [VerfasserIn]  |
| Jensen, Alexandra [VerfasserIn]  |
| Herfarth, Klaus [VerfasserIn]  |
| Debus, Jürgen [VerfasserIn]  |
| Adeberg, Sebastian [VerfasserIn]  |
Titel: | The role of organ- and function-preserving radiotherapy in the treatment of adenoid cystic carcinoma of the larynx |
Verf.angabe: | Sati Akbaba, Kristin Lang, Olcay Cem Bulut, Thomas Held, Stefan Rieken, Peter Plinkert, Alexandra Jensen, Klaus Herfarth, Juergen Debus, Sebastian Adeberg |
Jahr: | 2019 |
Umfang: | 7 S. |
Fussnoten: | Gesehen am 15.10.2019 |
Titel Quelle: | Enthalten in: Head & neck |
Ort Quelle: | New York, NY [u.a.] : Wiley Interscience, 1979 |
Jahr Quelle: | 2019 |
Band/Heft Quelle: | 41(2019), 7, Seite 2208-2214 |
ISSN Quelle: | 1097-0347 |
Abstract: | BACKGROUND: To evaluate clinical outcome and functional larynx preservation after radiotherapy (RT) for adenoid cystic carcinoma (ACC) of the larynx. - METHODS: Eleven patients with primary ACC of the larynx, who received RT definitely (n = 5/11) or postoperatively (n = 6/11), were analyzed regarding survival and treatment-related toxicity with the focus on functional larynx preservation. - RESULTS: Median follow-up was 45 months. RT offered an excellent 5-year local control (LC) rate of 100%. Eight of 11 patients were treated with a laryngeal preservation approach (LPA). At last follow-up, only one of these eight patients developed a local recurrence requiring a total laryngectomy 11 years after treatment. Severe toxicity was uncommon, with only one patient with LPA, requiring a temporary tracheostomy during therapy. - CONCLUSIONS: RT is an effective treatment method for laryngeal ACC with excellent LC rates, preservation of the laryngeal function and voice formation, representing a valuable therapy alternative to total laryngectomy. |
DOI: | doi:10.1002/hed.25678 |
URL: | Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.
DOI: https://doi.org/10.1002/hed.25678 |
Datenträger: | Online-Ressource |
Sprache: | eng |
Sach-SW: | ACC |
| carbon ion |
| intensity modulated radiotherapy |
| larynx |
| larynx preservation |
K10plus-PPN: | 1678927309 |
Verknüpfungen: | → Zeitschrift |
¬The¬ role of organ- and function-preserving radiotherapy in the treatment of adenoid cystic carcinoma of the larynx / Akbaba, Sati [VerfasserIn]; 2019 (Online-Ressource)