| |  Online-Ressource |
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| Verfasst von: | Akbaba, Sati [VerfasserIn]  |
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| | Uzun-Lang, Kristin [VerfasserIn] |
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| | Bulut, Cem [VerfasserIn] |
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| | Held, Thomas [VerfasserIn] |
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| | Rieken, Stefan [VerfasserIn] |
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| | Plinkert, Peter K. [VerfasserIn] |
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| | Jensen, Alexandra [VerfasserIn] |
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| | Herfarth, Klaus [VerfasserIn] |
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| | Debus, Jürgen [VerfasserIn] |
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| | Adeberg, Sebastian [VerfasserIn] |
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| Titel: | The role of organ- and function-preserving radiotherapy in the treatment of adenoid cystic carcinoma of the larynx |
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| Verf.angabe: | Sati Akbaba, Kristin Lang, Olcay Cem Bulut, Thomas Held, Stefan Rieken, Peter Plinkert, Alexandra Jensen, Klaus Herfarth, Juergen Debus, Sebastian Adeberg |
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| Jahr: | 2019 |
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| Umfang: | 7 S. |
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| Fussnoten: | Gesehen am 15.10.2019 |
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| Titel Quelle: | Enthalten in: Head & neck |
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| Ort Quelle: | New York, NY [u.a.] : Wiley Interscience, 1979 |
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| Jahr Quelle: | 2019 |
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| Band/Heft Quelle: | 41(2019), 7, Seite 2208-2214 |
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| ISSN Quelle: | 1097-0347 |
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| Abstract: | BACKGROUND: To evaluate clinical outcome and functional larynx preservation after radiotherapy (RT) for adenoid cystic carcinoma (ACC) of the larynx. - METHODS: Eleven patients with primary ACC of the larynx, who received RT definitely (n = 5/11) or postoperatively (n = 6/11), were analyzed regarding survival and treatment-related toxicity with the focus on functional larynx preservation. - RESULTS: Median follow-up was 45 months. RT offered an excellent 5-year local control (LC) rate of 100%. Eight of 11 patients were treated with a laryngeal preservation approach (LPA). At last follow-up, only one of these eight patients developed a local recurrence requiring a total laryngectomy 11 years after treatment. Severe toxicity was uncommon, with only one patient with LPA, requiring a temporary tracheostomy during therapy. - CONCLUSIONS: RT is an effective treatment method for laryngeal ACC with excellent LC rates, preservation of the laryngeal function and voice formation, representing a valuable therapy alternative to total laryngectomy. |
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| DOI: | doi:10.1002/hed.25678 |
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| URL: | Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.
DOI: https://doi.org/10.1002/hed.25678 |
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| Datenträger: | Online-Ressource |
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| Sprache: | eng |
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| Sach-SW: | ACC |
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| | carbon ion |
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| | intensity modulated radiotherapy |
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| | larynx |
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| | larynx preservation |
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| K10plus-PPN: | 1678927309 |
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| Verknüpfungen: | → Zeitschrift |
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¬The¬ role of organ- and function-preserving radiotherapy in the treatment of adenoid cystic carcinoma of the larynx / Akbaba, Sati [VerfasserIn]; 2019 (Online-Ressource)
