A rare cause for lower back pain

• Verfasst von: Löffler, Christian [VerfasserIn]
• Verfasst von: Hoffend, Johannes [VerfasserIn]
• Verfasst von: Rebel, Martin [VerfasserIn]
• Verfasst von: Waldherr, Rüdiger [VerfasserIn]
• Verfasst von: Bergner, Raoul [VerfasserIn]
• Titel: A rare cause for lower back pain
• Titelzusatz: a case of an IgG4-related periaortitis
• Mitwirkende: Uppenkamp, Michael
• Verf.angabe: Christian Löffler, Johannes Hoffend, Martin Rebel, Rüdiger Waldherr, Michael Uppenkamp, Raoul Bergner
• Jahr: 2016
• Umfang: 6 S.
• Fussnoten: Gesehen am 21.10.2019 ; Published online: 23 February 2014
• Titel Quelle: Enthalten in: Clinical rheumatology
• Ort Quelle: London : Springer, 1982
• Jahr Quelle: 2016
• Band/Heft Quelle: 35(2016), 1, Seite 265-270
• ISSN Quelle: 1434-9949
• DOI: doi:10.1007/s10067-014-2535-0
• Datenträger: Online-Ressource
• Sprache: eng
• Sach-SW: Aortitis
• Sach-SW: Azathioprine
• Sach-SW: IgG4
• Sach-SW: PET/CT
• Sach-SW: Steroids
• Sach-SW: Therapy
• K10plus-PPN: 1679240196

Abstract

IgG4-related disease (IgG4-RD) are a group of autoinflammatory diseases often presenting as tumor-like lesions because of their infiltrative or mass forming behavior. They are characterized by a typical histology consisting of storiform fibrosis, high numbers of infiltrating IgG4-positive plasma cells, obliterative phlebitis, and a moderate presence of eosinophilic cells. Serum IgG4 levels can be elevated. We present a case of a 57 year-old male patient with immobilizing lower back pain, fever, and night sweats. We diagnosed IgG4-related periaortitis using serum IgG4 levels, abdominal ultrasound, PET/CT, and histology. We successfully treated the patient with glucocorticoids (GC) and azathioprine. Periaortitis is a rare presentation of IgG4-RD and therefore noteworthy. It has to be considered in patients with a retroperitoneal mass.