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Verfasst von:Förster, Alex [VerfasserIn]   i
 Al-Zghloul, Mansour [VerfasserIn]   i
 Wenz, Holger [VerfasserIn]   i
 Böhme, Johannes [VerfasserIn]   i
 Groden, Christoph [VerfasserIn]   i
 Alonso, Angelika [VerfasserIn]   i
Titel:Gadolinium leakage in ocular structures is common in lacunar infarction
Verf.angabe:Alex Förster, Mansour Al-Zghloul, Holger Wenz, Johannes Böhme, Christoph Groden, Angelika Alonso
Jahr:2019
Jahr des Originals:2018
Umfang:3 S.
Fussnoten:Originally published November 21, 2018 ; Gesehen am 23.10.2019
Titel Quelle:Enthalten in: Stroke
Ort Quelle:New York, NY : Association, 1970
Jahr Quelle:2019
Band/Heft Quelle:50(2019), 1, Seite 193-195
ISSN Quelle:1524-4628
Abstract:Background and Purpose - We investigated the frequency and pattern of blood-brain barrier, as well as blood-retina barrier, impairment in acute lacunar infarction as demonstrated by hyperintense acute reperfusion marker and gadolinium leakage in ocular structures (GLOS), respectively, on fluid-attenuated inversion recovery images.Methods - Acute lacunar infarction patients who underwent repeated magnetic resonance imaging after intravenous contrast agent administration were identified and the presence of GLOS in the anterior chamber and vitreous body and hyperintense acute reperfusion marker noted on fluid-attenuated inversion recovery.Results - Overall, 24 acute lacunar infarction patients (median age 64.5 years; interquartile range, 54-78 years) were included. On contrast-enhanced fluid-attenuated inversion recovery, GLOS was observed in 11 (45.8%) patients: in 4 (16.7%) in the anterior chamber only and in 7 (29.2%) in the anterior chamber and vitreous body. In all patients, GLOS was bilateral and symmetrical. In patients with GLOS in the anterior chamber only, the time between initial and follow-up magnetic resonance imaging was significantly shorter (7.5 [interquartile range, 4.25-11.5] hours) compared with patients with GLOS in the anterior chamber and vitreous body (28 [interquartile range, 10-43] hours; P=0.047). Hyperintense acute reperfusion marker could not be demonstrated in any of the patients.Conclusions - In acute lacunar infarction patients, unlike hyperintense acute reperfusion marker, GLOS is a frequent finding and shows a similar temporal evolution like in larger ischemic stroke.
DOI:doi:10.1161/STROKEAHA.118.023573
URL:Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.

Volltext: https://doi.org/10.1161/STROKEAHA.118.023573
 Verlag: https://www.ahajournals.org/doi/10.1161/STROKEAHA.118.023573
 DOI: https://doi.org/10.1161/STROKEAHA.118.023573
Datenträger:Online-Ressource
Sprache:eng
K10plus-PPN:1679456784
Verknüpfungen:→ Zeitschrift

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