Online-Ressource | |
Verfasst von: | Stahl, Mirjam [VerfasserIn] |
Holfelder, Christian [VerfasserIn] | |
Kneppo, Carolin [VerfasserIn] | |
Kieser, Meinhard [VerfasserIn] | |
Kasperk, Christian [VerfasserIn] | |
Schönau, Eckhard [VerfasserIn] | |
Sommerburg, Olaf [VerfasserIn] | |
Tönshoff, Burkhard [VerfasserIn] | |
Titel: | Multiple prevalent fractures in relation to macroscopic bone architecture in patients with cystic fibrosis |
Verf.angabe: | Mirjam Stahl, Christian Holfelder, Carolin Kneppo, Meinhard Kieser, Christian Kasperk, Eckhard Schoenau, Olaf Sommerburg, Burkhard Tönshoff |
E-Jahr: | 2018 |
Jahr: | [January 2018] |
Umfang: | 7 S. |
Illustrationen: | Diagramme |
Fussnoten: | Gesehen am 04.11.2019 |
Titel Quelle: | Enthalten in: Journal of cystic fibrosis |
Ort Quelle: | Amsterdam [u.a.] : Elsevier Science, 2002 |
Jahr Quelle: | 2018 |
Band/Heft Quelle: | 17(2018), 1, Seite 114-120 |
ISSN Quelle: | 1873-5010 |
Abstract: | Background - The relative risk for bone fractures in patients with cystic fibrosis (CF) and its relationship to macroscopic bone architecture assessed by pQCT and DXA are incompletely defined. - Methods - In a cross-sectional study of 43 CF patients (age, 17.8±6.2years), rate and location of fractures, bone mass, density, geometry, and strength of the radius as well as forearm muscle size were investigated. - Results - The fracture rate in CF was 9.2-fold higher compared to an age-matched German control population. The probability of remaining free of any fracture in CF patients at 25years was reduced to 39.8% compared to 84.6% in controls (P<0.001). Assessment of macroscopic bone architecture by DXA and pQCT allowed the differentiation of patients with multiple prevalent fractures with a high sensitivity (up to 100%) and specificity (up to 94.3%). - Conclusions - Bone densitometry is a useful tool for noninvasive assessment of fracture risk in CF patients. |
DOI: | doi:10.1016/j.jcf.2016.06.004 |
URL: | Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt. Volltext ; Verlag: https://doi.org/10.1016/j.jcf.2016.06.004 |
Volltext: http://www.sciencedirect.com/science/article/pii/S1569199316305471 | |
DOI: https://doi.org/10.1016/j.jcf.2016.06.004 | |
Datenträger: | Online-Ressource |
Sprache: | eng |
Sach-SW: | Bone densitometry |
Bone disease | |
Cystic fibrosis | |
Fracture rate | |
Macroscopic bone architecture | |
Noninvasive monitoring | |
K10plus-PPN: | 1680869051 |
Verknüpfungen: | → Zeitschrift |