A worldwide comparison of the management of surgical treatment of advanced oral cancer

• Verfasst von: Kansy, Julia Katharina [VerfasserIn]
• Verfasst von: Mueller, Andreas Albert [VerfasserIn]
• Verfasst von: Mücke, Thomas [VerfasserIn]
• Verfasst von: Körsgen, Friederike [VerfasserIn]
• Verfasst von: Wolff, Klaus Dietrich [VerfasserIn]
• Verfasst von: Zeilhofer, Hans-Florian [VerfasserIn]
• Verfasst von: Hölzle, Frank [VerfasserIn]
• Verfasst von: Pradel, Winnie [VerfasserIn]
• Verfasst von: Schneider, Matthias [VerfasserIn]
• Verfasst von: Kolk, Andreas [VerfasserIn]
• Verfasst von: Smeets, Ralf [VerfasserIn]
• Verfasst von: Acero, Julio [VerfasserIn]
• Verfasst von: Haers, Piet [VerfasserIn]
• Verfasst von: Ghali, G. E. [VerfasserIn]
• Verfasst von: Hoffmann, Jürgen [VerfasserIn]
• Titel: A worldwide comparison of the management of surgical treatment of advanced oral cancer
• Verf.angabe: Katinka Kansy, Andreas Albert Mueller, Thomas Mücke, Friederike Koersgen, Klaus Dietrich Wolff, Hans-Florian Zeilhofer, Frank Hölzle, Winnie Pradel, Matthias Schneider, Andreas Kolk, Ralf Smeets, Julio Acero, Piet Haers, G. E. Ghali, Jürgen Hoffmann
• E-Jahr: 2018
• Jahr: 8 January 2018
• Umfang: 10 S.
• Fussnoten: Gesehen am 04.11.2019
• Titel Quelle: Enthalten in: Journal of cranio-maxillofacial surgery
• Ort Quelle: Oxford [u.a.] : Elsevier, 1987
• Jahr Quelle: 2018
• Band/Heft Quelle: 46(2018), 3, Seite 511-520
• ISSN Quelle: 1878-4119
• DOI: doi:10.1016/j.jcms.2017.12.031
• Datenträger: Online-Ressource
• Sprache: eng
• Sach-SW: Free tissue flaps
• Sach-SW: Mandible
• Sach-SW: Maxilla
• Sach-SW: Microsurgery
• Sach-SW: OSCC
• Sach-SW: Tongue cancer
• K10plus-PPN: 1680960326

Abstract

Introduction - Microvascular surgery following tumor resection has become an important field of oral and maxillofacial surgery (OMFS). Following the results from management of T1/T2 floor-of-mouth and tongue squamous cell carcinoma (SCC) in German-speaking countries, Europe, and worldwide, this paper presents specific concepts for the management of resection and reconstruction of T3/T4 SCC of the maxillary and mandibular alveolar process and tongue. - Methods - The DÖSAK questionnaire was distributed in three different phases to a growing number of maxillofacial units worldwide. Within this survey, clinical patient settings were presented to participants and center-specific treatment strategies were evaluated. - Results - A total of 188 OMFS units from 36 different countries documented their treatment strategies for T3/T4 maxillary and mandibular alveolar process and tongue SCC. The extent of surgical resections and subsequent reconstructions is more consistent than with T1/T2 tumors, although the controversy surrounding continuity resections and mandible-sparing procedures remains. For continuity resection of the mandible the fibula free flap is the most frequently used bone replacement, whereas maxilla reconstruction concepts are less consistent, ranging from locoregional coverage concepts and different microvascular reconstruction options to treatment via obturator prosthesis. - Conclusion - Results from treatment strategies for T3/T4 tumors underline the limited evidence for the appropriate amount of resection and subsequent reconstruction process, especially in cases involving the mandible. Prospective randomized trials will be necessary in the long term to establish valid treatment guidelines.