Short- and long-term incidence of thromboembolic events in Takotsubo Syndrome as compared with acute coronary syndrome

• Verfasst von: El-Battrawy, Ibrahim [VerfasserIn]
• Verfasst von: Gietzen, Thorsten [VerfasserIn]
• Verfasst von: Lang, Siegfried [VerfasserIn]
• Verfasst von: Ansari, Uzair [VerfasserIn]
• Verfasst von: Behnes, Michael [VerfasserIn]
• Verfasst von: Zhou, Xiao-Bo [VerfasserIn]
• Verfasst von: Borggrefe, Martin [VerfasserIn]
• Verfasst von: Akın, Ibrahim [VerfasserIn]
• Titel: Short- and long-term incidence of thromboembolic events in Takotsubo Syndrome as compared with acute coronary syndrome
• Verf.angabe: Ibrahim El-Battrawy, Thorsten Gietzen, Siegfried Lang, Uzair Ansari, Michael Behnes, Xiaobo Zhou, Martin Borggrefe, Ibrahim Akin
• E-Jahr: 2019
• Jahr: April 15, 2019
• Umfang: 6 S.
• Fussnoten: Gesehen am 05.11.2019
• Titel Quelle: Enthalten in: Angiology
• Ort Quelle: Thousand Oaks, Calif. [u.a.] : Sage, 1950
• Jahr Quelle: 2019
• Band/Heft Quelle: 70(2019), 9, Seite 838-843
• ISSN Quelle: 1940-1574
• DOI: doi:10.1177/0003319719842682
• Datenträger: Online-Ressource
• Sprache: eng
• K10plus-PPN: 1681073021

Abstract

Thromboembolic events are a common complication in Takotsubo syndrome (TTS). However, their long-term incidence compared with acute coronary syndrome (ACS) is lacking. In-hospital and long-term incidence of thromboembolic events of 138 consecutive patients with TTS were compared with 138 sex- and age-matched patients with ACS. Predictors of events were analyzed. The incidence of thromboembolic events in TTS was 2-fold higher than ACS (21% vs 9%; P < .01) over a mean follow-up of 5 years. Although the left ventricular ejection fraction (LVEF) at event was significantly lower in TTS compared with ACS (38% [9%] vs 54% [11%]; P < .01), the follow-up LVEF was comparable. Patients with TTS suffering from thromboembolic events were more often treated with anticoagulation compared with ACS (44.8% vs 8.3%, P = .03). However, more patients presenting with ACS (100% vs 48.3%; P < .01) were discharged on aspirin. Only elevated C-reactive protein was a predictor of thromboembolic events using multivariate analysis (hazard ratio 1.1, 95% confidence interval, 1.0-1.2; P < .01). In conclusion, the risk of thromboembolic events in TTS was significantly higher than the risk of thromboembolic events in ACS over a mean follow-up of 5 years.