Clinical features of Wilson disease

• Verfasst von: Stremmel, Wolfgang [VerfasserIn]
• Verfasst von: Merle, Uta [VerfasserIn]
• Verfasst von: Weiskirchen, Ralf [VerfasserIn]
• Titel: Clinical features of Wilson disease
• Verf.angabe: Wolfgang Stremmel, Uta Merle, Ralf Weiskirchen
• Jahr: 2019
• Umfang: 5 S.
• Fussnoten: Gesehen am 06.11.2019
• Titel Quelle: Enthalten in: Annals of translational medicine
• Ort Quelle: Shatin, NT : AME Publishing Company, 2013
• Jahr Quelle: 2019
• Band/Heft Quelle: 7(2019,S2) Artikel-Nummer S61, 5 Seiten
• ISSN Quelle: 2305-5847
• DOI: doi:10.21037/atm.2019.01.20
• Datenträger: Online-Ressource
• Sprache: eng
• K10plus-PPN: 1681203561

Abstract

Wilson disease (WD) presents often as a chameleon with a plethora of mild and discrete symptoms. As disease of young aged people, the clinical diagnosis is extremely difficult and misdiagnoses are frequent. Tremor, dysarthria and hepatomegaly sometimes suggest alcoholic liver disease which is a disaster for the patients. Due to the only moderate abnormality of liver function tests the disease is underestimated in its severity with a fatal prognosis when not adequately treated. Therefore, it is the challenge to consider WD as diagnosis, particularly in young patients with unclear liver disease, neuropsychiatric disorders or hemolysis.