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Verfasst von:Filippi, Massimo [VerfasserIn]   i
 Preziosa, Paolo [VerfasserIn]   i
 Banwell, Brenda L. [VerfasserIn]   i
 Barkhof, Frederik [VerfasserIn]   i
 Ciccarelli, Olga [VerfasserIn]   i
 De Stefano, Nicola [VerfasserIn]   i
 Geurts, Jeroen J. G. [VerfasserIn]   i
 Paul, Friedemann [VerfasserIn]   i
 Reich, Daniel S. [VerfasserIn]   i
 Toosy, Ahmed T. [VerfasserIn]   i
 Traboulsee, Anthony [VerfasserIn]   i
 Wattjes, Mike Peter [VerfasserIn]   i
 Yousry, Tarek A. [VerfasserIn]   i
 Gass, Achim [VerfasserIn]   i
 Lubetzki, Catherine [VerfasserIn]   i
 Weinshenker, Brian G. [VerfasserIn]   i
 Rocca, Maria A. [VerfasserIn]   i
Titel:Assessment of lesions on magnetic resonance imaging in multiple sclerosis
Titelzusatz:practical guidelines
Verf.angabe:Massimo Filippi, Paolo Preziosa, Brenda L. Banwell, Frederik Barkhof, Olga Ciccarelli, Nicola De Stefano, Jeroen J.G. Geurts, Friedemann Paul, Daniel S. Reich, Ahmed T. Toosy, Anthony Traboulsee, Mike P. Wattjes, Tarek A. Yousry, Achim Gass, Catherine Lubetzki, Brian G. Weinshenker and Maria A. Rocca
E-Jahr:2019
Jahr:17 June 2019
Umfang:18 S.
Fussnoten:Gesehen am 19.11.2019
Titel Quelle:Enthalten in: Brain
Ort Quelle:Oxford : Oxford Univ. Press, 1878
Jahr Quelle:2019
Band/Heft Quelle:142(2019), 7, Seite 1858-1875
ISSN Quelle:1460-2156
Abstract:MRI has improved the diagnostic work-up of multiple sclerosis, but inappropriate image interpretation and application of MRI diagnostic criteria contribute to misdiagnosis. Some diseases, now recognized as conditions distinct from multiple sclerosis, may satisfy the MRI criteria for multiple sclerosis (e.g. neuromyelitis optica spectrum disorders, Susac syndrome), thus making the diagnosis of multiple sclerosis more challenging, especially if biomarker testing (such as serum anti-AQP4 antibodies) is not informative. Improvements in MRI technology contribute and promise to better define the typical features of multiple sclerosis lesions (e.g. juxtacortical and periventricular location, cortical involvement). Greater understanding of some key aspects of multiple sclerosis pathobiology has allowed the identification of characteristics more specific to multiple sclerosis (e.g. central vein sign, subpial demyelination and lesional rims), which are not included in the current multiple sclerosis diagnostic criteria. In this review, we provide the clinicians and researchers with a practical guide to enhance the proper recognition of multiple sclerosis lesions, including a thorough definition and illustration of typical MRI features, as well as a discussion of red flags suggestive of alternative diagnoses. We also discuss the possible place of emerging qualitative features of lesions which may become important in the near future.
DOI:doi:10.1093/brain/awz144
URL:Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.

Volltext: https://doi.org/10.1093/brain/awz144
 Verlag: https://academic.oup.com/brain/article/142/7/1858/5519813
 DOI: https://doi.org/10.1093/brain/awz144
Datenträger:Online-Ressource
Sprache:eng
K10plus-PPN:1682093816
Verknüpfungen:→ Zeitschrift

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