| |  Online-Ressource |
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| Verfasst von: | Menze, Bjoern Holger [VerfasserIn]  |
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| | Weber, Marc-André [VerfasserIn] |
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| Titel: | A generative probabilistic model and discriminative extensions for brain lesion segmentation |
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| Titelzusatz: | with application to tumor and stroke |
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| Verf.angabe: | Bjoern H. Menze, Koen Van Leemput, Danial Lashkari, Tammy Riklin-Raviv, Ezequiel Geremia, Esther Alberts, Philipp Gruber, Susanne Wegener, Marc-André Weber, Gabor Székely, Nicholas Ayache, and Polina Golland |
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| Jahr: | 2016 |
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| Jahr des Originals: | 2015 |
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| Umfang: | 14 S. |
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| Fussnoten: | Date of Publication: 20 November 2015 ; Gesehen am 25.11.2019 |
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| Titel Quelle: | Enthalten in: Institute of Electrical and Electronics EngineersIEEE transactions on medical imaging |
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| Ort Quelle: | New York, NY : Institute of Electrical and Electronics Engineers, 1982 |
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| Jahr Quelle: | 2016 |
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| Band/Heft Quelle: | 35(2016), 4, Seite 933-946 |
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| ISSN Quelle: | 1558-254X |
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| Abstract: | We introduce a generative probabilistic model for segmentation of brain lesions in multi-dimensional images that generalizes the EM segmenter, a common approach for modelling brain images using Gaussian mixtures and a probabilistic tissue atlas that employs expectation-maximization (EM), to estimate the label map for a new image. Our model augments the probabilistic atlas of the healthy tissues with a latent atlas of the lesion. We derive an estimation algorithm with closed-form EM update equations. The method extracts a latent atlas prior distribution and the lesion posterior distributions jointly from the image data. It delineates lesion areas individually in each channel, allowing for differences in lesion appearance across modalities, an important feature of many brain tumor imaging sequences. We also propose discriminative model extensions to map the output of the generative model to arbitrary labels with semantic and biological meaning, such as “tumor core” or “fluid-filled structure”, but without a one-to-one correspondence to the hypo- or hyper-intense lesion areas identified by the generative model. We test the approach in two image sets: the publicly available BRATS set of glioma patient scans, and multimodal brain images of patients with acute and subacute ischemic stroke. We find the generative model that has been designed for tumor lesions to generalize well to stroke images, and the extended discriminative -discriminative model to be one of the top ranking methods in the BRATS evaluation. |
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| DOI: | doi:10.1109/TMI.2015.2502596 |
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| URL: | Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.
Volltext ; Verlag: https://doi.org/10.1109/TMI.2015.2502596 |
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| | Volltext: https://ieeexplore.ieee.org/document/7332941 |
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| | DOI: https://doi.org/10.1109/TMI.2015.2502596 |
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| Datenträger: | Online-Ressource |
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| Sprache: | eng |
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| Sach-SW: | acute ischemic stroke |
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| | Algorithms |
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| | anatomical structure |
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| | Bayes methods |
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| | Bayes Theorem |
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| | Biological system modeling |
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| | biomedical MRI |
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| | brain |
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| | brain lesion segmentation |
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| | Brain modeling |
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| | Brain Neoplasms |
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| | brain tumor imaging sequences |
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| | BRATS glioma patient scans |
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| | closed-form EM update equations |
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| | discriminative extensions |
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| | EM segmenter |
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| | expectation-maximization |
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| | extended discriminative -discriminative model |
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| | fluid-filled structure |
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| | Gaussian mixtures |
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| | Gaussian processes |
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| | generative probabilistic model |
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| | Humans |
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| | hyper-intense lesion |
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| | hypo-intense lesion |
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| | image segmentation |
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| | latent atlas prior distribution |
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| | lesion posterior distributions |
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| | Lesions |
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| | magnetic resonance imaging |
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| | Mathematical model |
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| | Medical diagnostic imaging |
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| | medical image processing |
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| | mixture models |
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| | Models, Statistical |
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| | MRI |
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| | multidimensional images |
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| | object segmentation |
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| | Probabilistic logic |
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| | probabilistic tissue atlas |
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| | Stroke |
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| | subacute ischemic stroke |
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| | tumor |
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| K10plus-PPN: | 1683461053 |
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| Verknüpfungen: | → Zeitschrift |
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¬A¬ generative probabilistic model and discriminative extensions for brain lesion segmentation / Menze, Bjoern Holger [VerfasserIn]; 2016 (Online-Ressource)
