Status: Bibliographieeintrag
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| |  Online-Ressource |
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| Verfasst von: | Wang, Xingsong [VerfasserIn]  |
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| | Herold, Christina [VerfasserIn] |
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| | Schröder, Johannes [VerfasserIn] |
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| Titel: | Associations between brain structural networks and neurological soft signs in healthy adults |
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| Verf.angabe: | Xingsong Wang, Christina J. Herold, Li Kong, Johannes Schroeder |
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| E-Jahr: | 2019 |
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| Jahr: | 12 October 2019 |
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| Umfang: | 7 S. |
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| Fussnoten: | Gesehen am 26.11.2019 |
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| Titel Quelle: | Enthalten in: Psychiatry research. Neuroimaging |
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| Ort Quelle: | Amsterdam : Elsevier, 2016 |
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| Jahr Quelle: | 2019 |
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| Band/Heft Quelle: | 293(2019), Artikel-ID 110989, Seite 1-7 |
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| ISSN Quelle: | 1872-7506 |
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| Abstract: | Neurological soft signs (NSS), as minor neurological deficits, have been identified in several psychiatric disorders, especially in schizophrenia. However, it's unclear how the neuropathological processes of the disease affect NSS related brain morphological changes and whether it is confounded by the use of medication. As NSS also exist in healthy people, the potential confounding effects of psychopathology or medication will be excluded if NSS are investigated in healthy people. Therefore, we applied a novel multivariate approach, source-based morphometry (SBM), to study structural networks in relation to NSS in healthy adults based on structural magnetic resonance imaging (MRI) data. The Heidelberg Scale was applied to evaluate NSS. Using SBM, we constructed structural networks and investigated their associations with NSS in healthy adults. Six grey matter (GM) structural networks were identified. Sensory integration subscores were associated with the cerebellar component and the cortico-basal ganglia-thalamic component. Motor coordination subscores and total NSS scores were associated with the sensorimotor component. The present findings indicated that structural network abnormalities in cerebellar, subcortical and cortical sensorimotor areas contribute to NSS performance in healthy adults. |
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| DOI: | doi:10.1016/j.pscychresns.2019.110989 |
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| URL: | Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.
Volltext ; Verlag ; Resolving-System: https://doi.org/10.1016/j.pscychresns.2019.110989 |
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| | Volltext: http://www.sciencedirect.com/science/article/pii/S0925492719301908 |
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| | DOI: https://doi.org/10.1016/j.pscychresns.2019.110989 |
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| Datenträger: | Online-Ressource |
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| Sprache: | eng |
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| Sach-SW: | Cerebellum |
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| | Healthy adults |
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| | Neurological soft signs |
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| | Sensorimotor areas |
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| | Source-based morphometry |
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| | Structural networks |
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| K10plus-PPN: | 1683530969 |
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| Verknüpfungen: | → Zeitschrift |
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Associations between brain structural networks and neurological soft signs in healthy adults / Wang, Xingsong [VerfasserIn]; 12 October 2019 (Online-Ressource)
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