Longitudinal evaluation of plasma concentrations of presepsin in patients after severe trauma

• Verfasst von: Koch, Christian [VerfasserIn]
• Verfasst von: Weigand, Markus A. [VerfasserIn]
• Verfasst von: Uhle, Florian [VerfasserIn]
• Titel: Longitudinal evaluation of plasma concentrations of presepsin in patients after severe trauma
• Titelzusatz: a prospective observational study
• Verf.angabe: Christian Koch, Sophie Ruhrmann, Michael Pöhlmann, Emmanuel Schneck, Borros Arneth, Thomas Zajonz, Michael Sander, Markus A. Weigand, Florian Uhle
• E-Jahr: 2018
• Jahr: 1 Jul 2018
• Umfang: 8 S.
• Fussnoten: Gesehen am 27.11.2019
• Titel Quelle: Enthalten in: Surgical infections
• Ort Quelle: Larchmont, NY : Liebert, 2000
• Jahr Quelle: 2018
• Band/Heft Quelle: 19(2018), 5, Seite 480-487
• ISSN Quelle: 1557-8674
• DOI: doi:10.1089/sur.2017.266
• Datenträger: Online-Ressource
• Sprache: eng
• K10plus-PPN: 1683639987

Abstract

The high mortality rate of patients suffering from severe trauma is based not only on the mechanism of injury, but also on the higher risk for development of subsequent infections. Therefore, the early recognition of infection after severe trauma is of particular importance for patient outcome. However, early diagnosis is often masked by the consequences of the sterile, damage-triggered immune response. Our study sought to analyze the course of soluble CD14-subtype (sCD14-ST, presepsin) compared with clinically established inflammatory and infectious biomarkers in a cohort of patients with severe trauma.