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Verfasst von:Rubeis, Giovanni [VerfasserIn]   i
 Steger, Florian [VerfasserIn]   i
Titel:Ethische und konzeptuelle Aspekte des Mitochondrien-Transfers („Drei-Eltern-Kind“)
Verf.angabe:Giovanni Rubeis, Florian Steger
E-Jahr:2019
Jahr:21 March 2019
Umfang:16 S.
Fussnoten:Gesehen am 05.12.2019
Titel Quelle:Enthalten in: Ethik in der Medizin
Ort Quelle:Berlin : Springer, 1998
Jahr Quelle:2019
Band/Heft Quelle:31(2019), 2, Seite 143-158
ISSN Quelle:1437-1618
Abstract:Definition of the problem: Although mitochondrial replacement techniques have been performed in humans and have been legalized in the UK, three crucial conceptual questions are yet unanswered: (1) Are mitochondrial replacement techniques a germline intervention? (2) Are mitochondrial replacement techniques a medically indicated therapy or an elective procedure of assisted reproduction? (3) What are the concepts of parenthood and identity behind mitochondrial replacement techniques? In our paper, we show that the ethical assessment of the procedure depends on the conceptual framing.ArgumentsThe procedure is an intervention in the germline, which makes it necessary to include future generations in the risk assessment. The procedure has to be regarded as an elective assisted reproduction technique since there is no medical necessity for its application. This is especially important when it comes to public funding for the clinical application. The term “three-parent child” is incorrect and misleading. It implies an outdated concept of parenthood that relies solely on genetic relatedness. Hence, the negative consequences for the future child’s psychosocial development as well as for family dynamics that are stated by some commentators are unfounded.ConclusionThe clarification of the three conceptual issues allows a sound ethical assessment. We conclude that the clinical implementation of mitochondrial replacement techniques is ethically acceptable as long as the safety of the procedure is further improved and it is implemented as an elective procedure of assisted reproduction without entitlement to public funding.
DOI:doi:10.1007/s00481-019-00523-8
URL:Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.

Volltext ; Verlag: http://dx.doi.org/10.1007/s00481-019-00523-8
 Volltext: https://doi.org/10.1007/s00481-019-00523-8
 DOI: https://doi.org/10.1007/s00481-019-00523-8
Datenträger:Online-Ressource
Sprache:ger
Sach-SW:Assisted reproduction
 Assistierte Reproduktion
 Drei-Eltern-Kind
 Elternschaft
 Intervention in the germline
 Keimbahnintervention
 Mitochondrial replacement therapy
 Mitochondrien-Transfer
 Parenthood
 Reproductive autonomy
 Reproduktive Selbstbestimmung
 Three-parent child
K10plus-PPN:1684391962
Verknüpfungen:→ Zeitschrift

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