The reimplantation valve-sparing aortic root replacement technique for patients with Marfan syndrome

• Verfasst von: Kremer, Jamila [VerfasserIn]
• Verfasst von: Farag, Mina [VerfasserIn]
• Verfasst von: Zaradzki, Marcin [VerfasserIn]
• Verfasst von: Szabó, Gábor [VerfasserIn]
• Verfasst von: Ruhparwar, Arjang [VerfasserIn]
• Verfasst von: Kallenbach, Klaus [VerfasserIn]
• Verfasst von: Karck, Matthias [VerfasserIn]
• Verfasst von: Arif, Rawa [VerfasserIn]
• Titel: The reimplantation valve-sparing aortic root replacement technique for patients with Marfan syndrome
• Titelzusatz: a single-center experience
• Verf.angabe: Jamila Kremer, Mina Farag, Marcin Zaradzki, Gabor Szabó, Arjang Ruhparwar, Klaus Kallenbach, Matthias Karck & Rawa Arif
• E-Jahr: 2019
• Jahr: 19 August 2019
• Umfang: 8 S.
• Fussnoten: Gesehen am 05.12.2019
• Titel Quelle: Enthalten in: Scientific reports
• Ort Quelle: [London] : Macmillan Publishers Limited, part of Springer Nature, 2011
• Jahr Quelle: 2019
• Band/Heft Quelle: 9(2019) Artikel-Nummer 12021, 8 Seiten
• ISSN Quelle: 2045-2322
• DOI: doi:10.1038/s41598-019-48572-9
• Datenträger: Online-Ressource
• Sprache: eng
• K10plus-PPN: 1684419131

Abstract

Valve-sparing aortic root replacement (VSARR) through reimplantation technique is widely regarded as optimal surgical approach for Marfan syndrome (MFS) patients. Perioperative and long-term data from all MFS patients undergoing VSARR using David’s technique at our center from 2007-2018 were analyzed. We included 56 patients with a mean age of 32.3 ± 12.3 years. Logistic EuroSCORE was 7.96 ± 5.2. Among others concomitant surgical procedures included aortic arch surgery (8.9%), mitral valve repair (23.2%) and replacement (1.7%). There were no operative deaths, nor in-hospital-mortality. One patient underwent re-exploration for bleeding, dialysis and pacemaker implantation was required in one case each. There was no occurrence of low-output syndrome nor neurological complications. Significant gender differences were not found, except for intraoperative blood transfusion occurring significantly more often in the female gender (p = 0.009). Despite significantly longer procedural times, concomitant surgery did not negatively impact overall outcome. Freedom of reoperation of the aortic root was 100% at 1 year, 97.7% at 8 years. Until last follow-up (61 ± 38 month) all patients survived, with no evidence of endocarditis. We emphasize once more that VSARR using David’s procedure is a safe method for MFS patients with excellent long-term results even if concomitant procedures are performed.