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Verfasst von:Hickethier, Tilman [VerfasserIn]   i
 Chang, De-Hua [VerfasserIn]   i
Titel:Venous-phase chest CT with reduced contrast medium dose
Titelzusatz:utilization of spectral low keV monoenergetic images improves image quality
Verf.angabe:Tilman Hickethier, Jan Robert Kroeger, Simon Lennartz, Jonas Doerner, David Maintz, De-Hua Chang
Jahr:2020
Jahr des Originals:2019
Umfang:5 S.
Fussnoten:Available online 21 November 2019 ; Gesehen am 20.01.2020
Titel Quelle:Enthalten in: European journal of radiology
Ort Quelle:Amsterdam [u.a.] : Elsevier Science, 1990
Jahr Quelle:2020
Band/Heft Quelle:122(2020) Artikel-Nummer 108756, 5 Seiten
ISSN Quelle:1872-7727
Abstract:Purpose - Intravenous contrast administration is crucial in many CT examinations but also poses a potential risk to the patient. Monoenergetic images (MonoE) of dual-energy CT systems can virtually increase iodine attenuation and might improve image quality (IQ) if contrast dose is reduced. In this study, we investigated the influence of MonoE on lymph node (LN) delineation and IQ in chest CT examinations with significantly reduced contrast dose (50 %) of a novel dual-layer CT (DLCT). - Method - 30 patients with clinically indicated reduced contrast dose underwent venous-phase chest DLCT scans. Conventional polyenergetic (PolyE) and MonoE images at 40keV were calculated. The contrast difference of hilar lymph nodes (LN-CD) to the adjacent right pulmonary artery, their signal-to-noise (SNR) and contrast-to-noise-ratio (CNR) were determined. Subjective IQ was evaluated by 2 readers with respect to LN delineation and overall contrast enhancement (CE) using a 5-point-Likert-scale. - Results - LN-CD, SNR and CNR were significantly higher in MonoE than in PolyE images (LN-CD 92.3±37.9 vs. 33.1±14.5 HU, SNR 8.4±3.4 vs. 4.0±1.2, CNR 9.2±6.3 vs. 2.6±1.5; all p<0.01). The LN delineation (3.7±0.9 vs.1.8±0.7; p<0.01) and the CE (3.9±0.7 vs. 2.3±0.7; p<0.01) were rated significantly better for MonoE than for PolyE images. There was no MonoE examination classified as non-diagnostic. - Conclusions - Subjective and objective IQ parameters can be significantly improved for venous-phase chest CT examinations with reduced contrast doses by utilization of low-keV MonoE reconstructions. All MonoE images provided sufficient overall CE and therefore reduced contrast doses might be considered in a wider range of DLCT examinations and patients.
DOI:doi:10.1016/j.ejrad.2019.108756
URL:Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.

Volltext: https://doi.org/10.1016/j.ejrad.2019.108756
 Verlag: http://www.sciencedirect.com/science/article/pii/S0720048X19304061
 DOI: https://doi.org/10.1016/j.ejrad.2019.108756
Datenträger:Online-Ressource
Sprache:eng
Sach-SW:Chest
 Contrast media reduction
 CT
 Dual energy
 Dual layer
 Low contrast agent dose
K10plus-PPN:1687866856
Verknüpfungen:→ Zeitschrift

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