Online-Ressource | |
Verfasst von: | Zimmermann-Schlegel, Verena [VerfasserIn] |
Wild, Beate [VerfasserIn] | |
Nawroth, Peter Paul [VerfasserIn] | |
Kopf, Stefan [VerfasserIn] | |
Herzog, Wolfgang [VerfasserIn] | |
Hartmann, Mechthild [VerfasserIn] | |
Titel: | Impact of depression and psychosocial treatment on heart rate variability in patients with type 2 diabetes mellitus |
Titelzusatz: | an exploratory analysis based on the HEIDIS trial |
Verf.angabe: | Verena Zimmermann-Schlegel, Beate Wild, Peter Nawroth, Stefan Kopf, Wolfgang Herzog, Mechthild Hartmann |
E-Jahr: | 2019 |
Jahr: | Jun 2019 |
Umfang: | 10 S. |
Fussnoten: | Gesehen am 31.01.2020 |
Titel Quelle: | Enthalten in: Experimental and clinical endocrinology & diabetes |
Ort Quelle: | Stuttgart [u.a.] : Thieme, 1983 |
Jahr Quelle: | 2019 |
Band/Heft Quelle: | 127(2019), 6, Seite 367-376 |
ISSN Quelle: | 1439-3646 |
Abstract: | <p> <b>Objectives</b> To explore the impact of depression on heart rate (HR) and heart rate variability (HRV) as a marker of autonomic nervous system (ANS) impairment in depressed and non-depressed patients with advanced type 2 diabetes mellitus (T2DM) and to explore possible effects of an acceptance- and mindfulness-based group intervention (MBSR) on HR and HRV.</p> <p> <b>Methods</b> Alongside a prospective clinical trial, we collected demographic, psychosocial and clinical data from 113 chronic T2DM patients in a standardized setting. At baseline and after one year, depressive mood was assessed with the Patient Health Questionnaire (PHQ-9), and autonomic function was determined by measuring HR and HRV markers. A subsample was randomly assigned to take part in eight MBSR sessions.</p> <p> <b>Results</b> Of the 113 T2DM patients (77.9% men; mean age=58.8±7.0 years; diabetes duration 11.5±7.0 years), 33 showed clinically relevant depressive symptoms at baseline. In cross-sectional analysis, we found no association between depression and HR/HRV (all comparisons p>0.05). In prospective regression analysis depression did not predict follow-up scores of HRV. The patients who participated in the MBSR intervention showed a tendency toward improved parasympathetic control (RMSSD, CV, E-I-Ratio) with small-to-moderate effect sizes (d≤0.38).</p> <p> <b>Conclusions</b> Depression was not directly associated with cardiac autonomic control in this sample, but MBSR training may have positively influenced HR and HRV. In advanced diabetes, somatic and behavioral parameters seem to be more predictive than depression for the course of autonomic functioning, but the pathways remain unclear.</p> |
DOI: | doi:10.1055/s-0043-125445 |
URL: | Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt. Volltext ; Verlag: https://doi.org/10.1055/s-0043-125445 |
Volltext: http://www.thieme-connect.de/DOI/DOI?10.1055/s-0043-125445 | |
DOI: https://doi.org/10.1055/s-0043-125445 | |
Datenträger: | Online-Ressource |
Sprache: | eng |
K10plus-PPN: | 1689032596 |
Verknüpfungen: | → Zeitschrift |