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Verfasst von:Schatz, Ulrike [VerfasserIn]   i
 Fischer, Sabine [VerfasserIn]   i
 Müller, Gabriele [VerfasserIn]   i
 Tselmin, Sergey [VerfasserIn]   i
 Birkenfeld, Andreas L. [VerfasserIn]   i
 Julius, Ulrich [VerfasserIn]   i
 März, Winfried [VerfasserIn]   i
 Bornstein, Stefan R. [VerfasserIn]   i
Titel:Cardiovascular risk factors in patients with premature cardiovascular events attending the University of Dresden Lipid Clinic
Verf.angabe:Ulrike Schatz, Sabine Fischer, Gabriele Müller, Sergey Tselmin, Andreas L. Birkenfeld, Ulrich Julius, Winfried März, Stefan R. Bornstein
E-Jahr:2019
Jahr:6 December 2019
Umfang:6 S.
Fussnoten:Gesehen am 18.02.2020
Titel Quelle:Enthalten in: Atherosclerosis. Supplements
Ort Quelle:Amsterdam [u.a.] : Elsevier Science, 2000
Jahr Quelle:2019
Band/Heft Quelle:40(2019), Seite 94-99
ISSN Quelle:1878-5050
Abstract:Objectives: Despite improved treatment, premature cardiovascular (CV) events remain a major health problem. Aim of this study was to evaluate the patterns of risk factors in patients with premature CV events. Methods: CV risk factors (CVRF) were evaluated in 130 patients with a history of CV events (myocardial infarction, stroke, limb ischemia, stent and bypass intervention in any vessel bed) under 50 years of age attending our lipid clinic. Patients were also stratified according to their Lp(a) concentrations: group 1: 0-45nmol/l (<18mg/dl); group 2: >45-120nmol/l (>18-50mg/dl); group 3: >120nmol/l (>50mg/dl). Results: The most common risk factors in our patients were male sex (75%), current (61%) and previous smoking (9%), arterial hypertension (70%), and a positive family history of early CV events (54%) and hyperlipidemia (69%). Only 27% had a BMI >30kg/m2 and 14% had diabetes mellitus. 69% of patients with premature CV disease (CVD) showed Lp(a) levels>120nmol/l (>50mg/dl). Patients with the highest Lp(a) showed a tendency of more frequent positive family histories of hyperlipidemia. They had experienced their first CV event on average 3 years earlier than those with low Lp(a). CV events predominantly involved coronary arteries. 85% of patients experienced at least one coronary event. Conclusion: In patients with premature CV disease male sex, smoking, hypertension, a positive family history and elevated Lp(a) are the most important CV risk factors. Lp(a) should be considered in the management of young patients with CV disease.
DOI:doi:10.1016/j.atherosclerosissup.2019.08.044
URL:Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.

Volltext: https://doi.org/10.1016/j.atherosclerosissup.2019.08.044
 Verlag: http://www.sciencedirect.com/science/article/pii/S1567568819300674
 DOI: https://doi.org/10.1016/j.atherosclerosissup.2019.08.044
Datenträger:Online-Ressource
Sprache:eng
Sach-SW:Early myocardial infarction
 Lipoprotein(a)
 Premature atherosclerosis
 Premature cardiovascular events
K10plus-PPN:1690265477
Verknüpfungen:→ Zeitschrift

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