Neurovascular communication during CNS development

• Verfasst von: Paredes Ugarte, Isidora B. [VerfasserIn]
• Verfasst von: Himmels, Patricia [VerfasserIn]
• Verfasst von: Ruiz de Almodóvar, Carmen [VerfasserIn]
• Titel: Neurovascular communication during CNS development
• Verf.angabe: Isidora Paredes, Patricia Himmels, and Carmen Ruiz de Almodóvar
• E-Jahr: 2018
• Jahr: 9 April 2018
• Umfang: 23 S.
• Illustrationen: Illustrationen
• Fussnoten: Gesehen am 21.02.2020
• Titel Quelle: Enthalten in: Developmental cell
• Ort Quelle: Cambridge, Mass. : Cell Press, 2001
• Jahr Quelle: 2018
• Band/Heft Quelle: 45(2018), 1, Seite 10-32
• ISSN Quelle: 1878-1551
• DOI: doi:10.1016/j.devcel.2018.01.023
• Datenträger: Online-Ressource
• Sprache: eng
• Sach-SW: angiocrine cue
• Sach-SW: brain
• Sach-SW: CNS development
• Sach-SW: CNS vascularization
• Sach-SW: neurodevelopment
• Sach-SW: neurovascular communication
• Sach-SW: neurovascular link
• Sach-SW: retina
• Sach-SW: spinal cord
• Sach-SW: vascular control of neuronal development and function
• K10plus-PPN: 1690667508

Abstract

A precise communication between the nervous and the vascular systems is crucial for proper formation and function of the central nervous system (CNS). Interestingly, this communication does not only occur by neural cells regulating the growth and properties of the vasculature, but new studies show that blood vessels actively control different neurodevelopmental processes. Here, we review the current knowledge on how neurons in particular influence growing blood vessels during CNS development and on how vessels participate in shaping the neural compartment. We also review the identified molecular mechanisms of this bidirectional communication.