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Verfasst von:Jia, Jiying [VerfasserIn]   i
 Li, Kunhe [VerfasserIn]   i
 Hofmann, Andreas [VerfasserIn]   i
 Heermann, Dieter W. [VerfasserIn]   i
Titel:The effect of bending rigidity on polymers
Verf.angabe:Jiying Jia, Kunhe Li, Andreas Hofmann, and Dieter W. Heermann
E-Jahr:2019
Jahr:18 February 2019
Umfang:11 S.
Fussnoten:Gesehen am 27.02.2020
Titel Quelle:Enthalten in: Macromolecular theory and simulations
Ort Quelle:Weinheim : Wiley-VCH, 1992
Jahr Quelle:2019
Band/Heft Quelle:28(2019), 3, Seite 1800071
ISSN Quelle:1521-3919
Abstract:The conformations of chromatin are influenced by many factors. In the regulation of gene expression the bending rigidity of the chromatin polymer and its heterogeneity play an important role for the possible conformations. To elucidate this, the effect of bending rigidity as well as its heterogeneity on various polymer properties is investigated. In the context of chromatin organization, the contact probability is an important measure. It is analyzed whether there is any ambiguity in the definition of a contact. The results show that the contact probability does not depend on the range of contact in the limit of a large contour length between monomers. Further, the persistence length as a function of the bending rigidity is computed in the homogeneous and heterogeneous cases. The persistence length is systematically smaller in the heterogeneous case. Chromosomes are confined by each other in the nucleus and by looking at specific loci, the environment changes much more slowly than the local chromatin part. In conjunction with bending rigidity, polymers in rectangular confinements with several aspect ratios are simulated. Due to the spiraling behavior when the box size is small enough, an oscillation in the contact probability and the orientational correlation function is found.
DOI:doi:10.1002/mats.201800071
URL:Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.

Volltext ; Verlag: https://doi.org/10.1002/mats.201800071
 Volltext: https://onlinelibrary.wiley.com/doi/abs/10.1002/mats.201800071
 DOI: https://doi.org/10.1002/mats.201800071
Datenträger:Online-Ressource
Sprache:eng
Sach-SW:bending rigidity
 confinement
 contact probability
 heterogeneity
 polymer
K10plus-PPN:1691130877
Verknüpfungen:→ Zeitschrift

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