Quick flicks

• Verfasst von: Balint, Bettina [VerfasserIn]
• Titel: Quick flicks
• Titelzusatz: association of paroxysmal kinesigenic dyskinesia and tics
• Verf.angabe: Bettina Balint, Sarah Wiethoff, Davide Martino, Claudia del Gamba, Anna Latorre, Christos Ganos, Henry Houlden, and Kailash P. Bhatia
• E-Jahr: 2018
• Jahr: 06 April 2018
• Umfang: 4 S.
• Fussnoten: Gesehen am 03.04.2020
• Titel Quelle: Enthalten in: Movement disorders clinical practice
• Ort Quelle: New York, NY : Wiley, 2014
• Jahr Quelle: 2018
• Band/Heft Quelle: 5(2018), 3, Seite 317-320
• ISSN Quelle: 2330-1619
• DOI: doi:10.1002/mdc3.12615
• Datenträger: Online-Ressource
• Sprache: eng
• Sach-SW: paroxysmal kinesigenic dyskinesia (PKD)
• Sach-SW: PRRT2
• Sach-SW: tics
• K10plus-PPN: 169150498X

Abstract

Background: Paroxysmal kinesigenic dyskinesia (PKD) is a rare disorder characterised by brief attacks of chorea, dystonia, or mixed forms precipitated by sudden movement. Methods: Observational study with a cohort of 14 PKD patients and genetic testing for PRRT2 mutations. Results: In a series of 14 PKD patients seen in our clinic at the National Hospital of Neurology, Queen Square, from 2012-2017, we noted tics in 11 patients (79%), which stand in stark contrast to the estimated lifetime prevalence of tics estimated to reach 1%. Conclusions: The two reasons to point out this possible association are the clinical implications and the potential opportunity of a better understanding of shared pathophysiological mechanisms of neuronal hyperexcitability.