Navigation überspringen
Universitätsbibliothek Heidelberg
Status: Bibliographieeintrag

Verfügbarkeit
Standort: ---
Exemplare: ---
heiBIB
 Online-Ressource
Verfasst von:Schirmbeck, Frederike [VerfasserIn]   i
 Swets, Marije [VerfasserIn]   i
 Meijer, Carin J. [VerfasserIn]   i
 Zink, Mathias [VerfasserIn]   i
 de Haan, Lieuwe [VerfasserIn]   i
 Kahn, René S. [VerfasserIn]   i
 Os, Jim van [VerfasserIn]   i
 Bruggeman, Richard [VerfasserIn]   i
 Cahn, Wiepke [VerfasserIn]   i
 Bartels-Velthuis, Agna A. [VerfasserIn]   i
Titel:Obsessive-compulsive symptoms and overall psychopathology in psychotic disorders
Titelzusatz:longitudinal assessment of patients and siblings
Verf.angabe:Frederike Schirmbeck, Marije Swets, Carin J. Meijer, Mathias Zink, Lieuwe de Haan, René S. Kahn, Jim van Os, Richard Bruggeman, Wiepke Cahn, Agna A. Bartels-Velthuis, Inez Myin-Germeys, GROUP investigators
E-Jahr:2018
Jahr:17 December 2016
Jahr des Originals:2016
Umfang:11 S.
Fussnoten:Published17 December 2016 ; Gesehen am 17.03.2020
Titel Quelle:Enthalten in: European archives of psychiatry and clinical neuroscience
Ort Quelle:Darmstadt : Steinkopff, 1868
Jahr Quelle:2018
Band/Heft Quelle:268(2018), 3, Seite 279-289
ISSN Quelle:1433-8491
Abstract:The course of obsessive-compulsive symptoms (OCS) and its association with alterations in other clinical variables in patients with psychotic disorders is insufficiently known. Patients (n = 602) and unaffected siblings (n = 652) from the Dutch Genetic Risk and Outcome of Psychosis (GROUP) study were investigated at baseline and after 3 years. Participants were assigned to four groups based on the course of OCS over time: no-OCS, persistent OCS, initial OCS and de novo OCS. In addition to cross-sectional comparisons, longitudinal associations between changes in OCS and symptoms of schizophrenia and general functioning were investigated. Patients with co-occurring OCS reported significantly higher severity of psychotic and affective symptoms as well as lower overall functioning compared to patients without OCS. These differences were stable over time for patients reporting persistent OCS. Subsequent repeated measure analysis revealed significant interaction effects for groups reporting changes in their OCS. Whereas the group with remission of initial OCS showed significant improvement in positive symptoms, emotional distress and functioning, the de novo group showed no significant change in these variables, but rather reported stable higher psychopathology. Similar results were found on a subclinical level in siblings. Patients with co-occurring OCS present a more severe clinical picture, especially if symptoms persist over time. The remission of OCS was associated with overall improvement, whereas individuals with de novo OCS already reported higher clinical impairment before OCS onset. More research is needed to elucidate causal pathways and to develop effective interventions for persistent comorbid OCS.
DOI:doi:10.1007/s00406-016-0751-0
URL:Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.

Volltext: https://doi.org/10.1007/s00406-016-0751-0
 DOI: https://doi.org/10.1007/s00406-016-0751-0
Datenträger:Online-Ressource
Sprache:eng
K10plus-PPN:1692705237
Verknüpfungen:→ Zeitschrift

Permanenter Link auf diesen Titel (bookmarkfähig):  https://katalog.ub.uni-heidelberg.de/titel/68533758   QR-Code
zum Seitenanfang