HIV self-test performance among female sex workers in Kampala, Uganda

• Verfasst von: Ortblad, Katrina [VerfasserIn]
• Verfasst von: Musoke, Daniel Kibuuka [VerfasserIn]
• Verfasst von: Ngabirano, Thomson [VerfasserIn]
• Verfasst von: Nakitende, Aidah [VerfasserIn]
• Verfasst von: Taasi, Geoffrey [VerfasserIn]
• Verfasst von: Barresi, Leah G. [VerfasserIn]
• Verfasst von: Bärnighausen, Till [VerfasserIn]
• Verfasst von: Oldenburg, Catherine E. [VerfasserIn]
• Titel: HIV self-test performance among female sex workers in Kampala, Uganda
• Titelzusatz: a cross-sectional study
• Verf.angabe: Katrina F. Ortblad, Daniel Kibuuka Musoke, Thomson Ngabirano, Aidah Nakitende, Geoffrey Taasi, Leah G. Barresi, Till Bärnighausen, Catherine E. Oldenburg
• Jahr: 2018
• Umfang: 7 S.
• Illustrationen: Diagramme
• Fussnoten: Gesehen am 24.03.2020
• Titel Quelle: Enthalten in: BMJ open
• Ort Quelle: London : BMJ Publishing Group, 2011
• Jahr Quelle: 2018
• Band/Heft Quelle: 8 (2018,11) Artikel-Nummer e022652, Seite 1-7
• ISSN Quelle: 2044-6055
• DOI: doi:10.1136/bmjopen-2018-022652
• Datenträger: Online-Ressource
• Sprache: eng
• Sach-SW: africa
• Sach-SW: female sex workers
• Sach-SW: HIV self-testing
• Sach-SW: performance
• Sach-SW: uganda
• K10plus-PPN: 1693168200

Abstract

Objective To evaluate HIV self-testing performance and results interpretation among female sex workers (FSWs) in Kampala, Uganda, who performed unassisted HIV self-testing. - Methods In October 2016, 104 participants used an oral HIV self-test while under observation by research assistants. Participants were not assisted on HIV self-test use prior to or during testing, and were only given the manufacturer’s pictorial and written instructions to guide them. Research assistants recorded if participants completed and/or had difficulties with steps in the HIV self-testing process on a prespecified checklist. Randomly drawn, used HIV self-tests were interpreted by FSWs. We calculated the concordance between FSWs’ interpretations of self-test results with those indicated in the manufacturer’s instructions. - Results Only 33% (34/104) of participants completed all of the key steps in the HIV self-testing process, and the majority (86%, 89/104) were observed having difficulties with at least one of these steps. Misinterpretation of HIV self-test results were common among FSWs: 23% (12/56) of FSWs interpreted HIV-negative self-test results as HIV positive and 8% (3/37) of FSWs interpreted HIV-positive self-test results as HIV negative. The concordance between FSWs’ interpretations of self-test results and that indicated in the instructions was 73% (95% CI 56% to 86%) for HIV-positive self-tests and 68% (95% CI 54% to 80%) for HIV-negative self-tests. - Conclusions FSWs in Kampala, who performed unassisted HIV self-testing, skipped steps in the HIV self-testing process and had difficulties correctly interpreting self-test results. Training on use and interpretation of HIV self-tests may be necessary to prevent errors in the HIV self-testing process and to avoid the negative consequences of false-positive and false-negative HIV self-test results among FSWs. - Trial registration number NCT02846402.