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Verfasst von:Pennesi, Marco [VerfasserIn]   i
 Amoroso, Stefano [VerfasserIn]   i
 Bassanese, Giulia [VerfasserIn]   i
 Pintaldi, Stefano [VerfasserIn]   i
 Giacomini, Giulia [VerfasserIn]   i
 Barbi, Egidio [VerfasserIn]   i
Titel:Frequency of urinary tract infection in children with antenatal diagnosis of urinary tract dilatation
Verf.angabe:Marco Pennesi, Stefano Amoroso, Giulia Bassanese, Stefano Pintaldi, Giulia Giacomini, Egidio Barbi
Jahr:2020
Jahr des Originals:2019
Umfang:4 S.
Fussnoten:Gesehen am 31.03.2020 ; Published online first 28 August 2019
Titel Quelle:Enthalten in: Archives of disease in childhood
Ort Quelle:London : BMJ Publ. Group, 1926
Jahr Quelle:2020
Band/Heft Quelle:105(2020), 3, Seite 260-263
ISSN Quelle:1468-2044
Abstract:Background Neonates with congenital urinary tract dilatation (UTD) may have an increased risk of urinary tract infections (UTI). At present, the management of these patients is controversial and the utility of continuous antibiotic prophylaxis (CAP) remains uncertain as the literature presents contradicting evidence. The aim of this observational study was to assess UTI occurrence in children with prenatal diagnosis of urinary collecting system dilatation without antibiotic prophylaxis. - Methods Between June 2012 and August 2016, we evaluated the incidence of UTI and the clinical and ultrasonography evolution in 407 children with a prenatally diagnosed UTD. All subjects underwent two prenatal ultrasounds scans (USs) at 20 weeks and 30 weeks of gestation and within 1 month of birth. Patients with a confirmed diagnosis of UTD underwent US follow-up at 6, 12 and 24 months of life. According to the UTD classification system stratify risk, after birth UTD were classified into three groups: UTD-P1 (low risk group), UTD-P2 (intermediate risk group), and UTD-P3 (high risk group). Voiding cystourethrogram was performed in all patients who presented a UTI and in those with UTD-P3. No patient underwent CAP. - Results Postnatal US confirmed UTD in 278 out of 428 patients with the following rates: UTD-P1 (126), UTD-P2 (95) and UTD-P3 (57). During postnatal follow-up, 6.83% patients presented a UTI (19 out of 278). Eleven out of 19 had vesicoureteral reflux (VUR), and other four were diagnosed with obstructive uropathy and underwent surgical correction. Five patients presented a UTI reinfection. - Conclusion The occurrence of UTI in patients with urinary collecting system dilatation was low. The recent literature reports an increased selection of multirestistant germs in patients with VUR exposed to CAP. This study constitutes a strong hint that routine continuous antibiotic prophylaxis could be avoided in patients with UTD.
DOI:doi:10.1136/archdischild-2019-317637
URL:Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.

Volltext ; Verlag: https://doi.org/10.1136/archdischild-2019-317637
 Volltext: https://adc.bmj.com/content/105/3/260
 DOI: https://doi.org/10.1136/archdischild-2019-317637
Datenträger:Online-Ressource
Sprache:eng
Sach-SW:Epidemiology
 Infectious Diseases
 Nephrology
 Urology
K10plus-PPN:1693573830
Verknüpfungen:→ Zeitschrift

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