| |  Online-Ressource |
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| Verfasst von: | Sprave, Tetyana [VerfasserIn]  |
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| | Verma, Vivek [VerfasserIn] |
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| | Förster, Robert [VerfasserIn] |
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| | Schlampp, Ingmar [VerfasserIn] |
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| | Bruckner, Thomas [VerfasserIn] |
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| | Bostel, Tilman [VerfasserIn] |
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| | El-Shafie, Rami [VerfasserIn] |
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| | Nicolay, Nils [VerfasserIn] |
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| | Debus, Jürgen [VerfasserIn] |
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| | Rief, Harald [VerfasserIn] |
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| Titel: | Quality of life following stereotactic body radiotherapy versus three-dimensional conformal radiotherapy for vertebral metastases |
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| Titelzusatz: | Secondary Analysis of an Exploratory Phase II Randomized Trial |
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| Verf.angabe: | Tanja Sprave, Vivek Verma, Robert Förster, Ingmar Schlampp, Thomas Bruckner, Tilman Bostel, Rami Ateayh El Shafie, Nils Henrik Nicolay, Jürgen Debus, Harald Rief |
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| E-Jahr: | 2018 |
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| Jahr: | August 2018 |
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| Umfang: | 8 S. |
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| Fussnoten: | Gesehen am 02.04.2020 |
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| Titel Quelle: | Enthalten in: Anticancer research |
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| Ort Quelle: | Attiki : [Verlag nicht ermittelbar], 2004 |
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| Jahr Quelle: | 2018 |
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| Band/Heft Quelle: | 38(2018), 8, Seite 4961-4968 |
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| ISSN Quelle: | 1791-7530 |
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| Abstract: | BACKGROUND/AIM: This was a prespecified secondary analysis of a randomized trial, which analyzed quality of life (QOL), fatigue, and emotional distress following stereotactic body radiotherapy (SBRT) versus conventional three-dimensional conformal radiotherapy (3DCRT) as part of palliative management of painful spinal metastases. - MATERIALS AND METHODS: Fifty-five patients were enrolled in this single-institutional randomized exploratory phase II trial (NCT02358720). Participants were randomly assigned to receive SBRT (single-fraction 24 Gy) or 3DCRT (30 Gy/10 fractions). QOL (EORTC QLQ-BM22), fatigue (EORTC QLQ FA13), and emotional distress (QSC-R10) at the end of radiotherapy, along with 3- and 6-month follow-up were assessed. - RESULTS: At all recorded time points, there were no significant QOL differences between cohorts, including painful sites, pain characteristics, functional impairment, or psychosocial aspects (p>0.05 for all). There were also no differences in all dimensions of fatigue between groups at each recorded time point (p>0.05 for all). Emotional distress was also similar at three (p=0.248) and six months (p=0.603). - CONCLUSION: Although these results demonstrate that SBRT does not cause worse QOL deteriorations compared to 3DCRT, larger randomized investigations are recommended to corroborate these findings. |
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| DOI: | doi:10.21873/anticanres.12814 |
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| URL: | Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.
Volltext: https://doi.org/10.21873/anticanres.12814 |
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| | DOI: https://doi.org/10.21873/anticanres.12814 |
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| Datenträger: | Online-Ressource |
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| Sprache: | eng |
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| Sach-SW: | Affective Symptoms |
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| | Breast Neoplasms |
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| | Cancer Pain |
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| | fatigue |
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| | Fatigue |
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| | Female |
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| | Humans |
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| | Kidney Neoplasms |
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| | Lung Neoplasms |
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| | Male |
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| | Middle Aged |
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| | Palliative Care |
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| | palliative radiotherapy |
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| | quality of life |
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| | Quality of Life |
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| | Radiosurgery |
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| | Radiotherapy, Conformal |
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| | Spinal Neoplasms |
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| | Spine metastases |
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| | stereotactic body radiation therapy |
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| | Surveys and Questionnaires |
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| K10plus-PPN: | 1693829355 |
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| Verknüpfungen: | → Zeitschrift |
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Quality of life following stereotactic body radiotherapy versus three-dimensional conformal radiotherapy for vertebral metastases / Sprave, Tetyana [VerfasserIn]; August 2018 (Online-Ressource)
